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FACTOR B, HUMAN

市场价：: 0.00

促销价：: ¥0.00

货号：341262-250UG

品牌：Millipore 密理博

配送至：

北京朝阳

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数量：

EA (预计3-5工作日到货)

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Replacement Information

Description
Overview	Native factor B from human serum. Single-chain glycoprotein present in normal human serum at about 200 µg/ml. During activation of complement via the alternative pathway, Factor B is cleaved and thus activated by Factor D into two fragments of M.W. of 30 kDa (Ba) and 63 kDa (Bb). The Bb fragment contains the serine protease enzymatic active site. The activated Bb fragment continues activation via the alternative pathway by cleaving, and thus activating, C3 and C5.
Catalogue Number	341262
Brand Family	Calbiochem®
Synonyms	C3 Proactivator

References
References	Kam, C.M., et al. 1987. J. Biol. Chem. 262, 3444. Gotze, O. and Muller-Eberhard, H.J. 1971. J. Exp. Med. 134, 90s.

Product Information
Form	Liquid
Formulation	In PBS, pH 7.2.

Applications

Biological Information
Biological activity	≥1,200 Factor BH50 units/mg; ≥50% of Factor B activity in NHS (mg/mg basis)
Purity	≥90% by SDS-PAGE
Source	Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Physicochemical Information
Contaminants	IgG, IgA, IgM, C3, C4, Factor H, Factor I, or albumin (Ouchterlony): ≤trace amounts

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Dry Ice Only
Toxicity	Standard Handling
Storage	≤ -70°C
Avoid freeze/thaw	Avoid freeze/thaw
Do not freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-70°C).

Packaging Information

Transport Information

Supplemental Information

Specifications

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