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Qiagen 凯杰 Biosharp Omega

首页细胞生物学检测Millipore 密理博>

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NGF 7S, mouse

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号:01-170

牌:Millipore 密理博

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Replacement Information

重要规格表

Key Applications Species Source
CULT Mouse Male mouse submaxillary glands
Description
Catalogue Number 01-170
Brand Family Upstate
Trade Name
  • Upstate
Description NGF 7S Protein, mouse
References
Product Information
Presentation Lyophilized.
Applications
Application The mouse NGF 7S Protein( or nerve growth factor 7S) is available in a 100 µg format.
Key Applications
  • Cell Culture
Biological Information
Source Male mouse submaxillary glands
Entrez Gene Number
Entrez Gene Summary This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis.
Gene Symbol
  • NGFB
  • HSAN5
  • NGF
  • Beta-NGF
  • MGC161426
  • MGC161428
Purification Method Sterilized through a 0.2 micron membrane filter
UniProt Number
UniProt Summary FUNCTION: SwissProt: P01138 # Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons.
SIZE: 241 amino acids; 26959 Da
SUBUNIT: Homodimer.
SUBCELLULAR LOCATION: Secreted.
DISEASE: SwissProt: P01138 # Defects in NGFB are the cause of hereditary sensory and autonomic neuropathy type 5 (HSAN5) [MIM:608654]. Hereditary sensory and autonomic neuropathies are characterized by loss of pain sensation in combination with other sensory and/or autonomic abnormalities. HSAN5 patients manifest loss of pain perception and impaired temperature sensitivity, ulcers, and in some cases self- mutilation. The autonomic involvement is variable.
SIMILARITY: SwissProt: P01138 ## Belongs to the NGF-beta family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Packaging Information
Material Size 100 µg
Transport Information
Supplemental Information
Specifications

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