[关闭]
您好!欢迎来到炼石商城   请登录  注册    兼职小伙伴  
我的购物车
0
Qiagen 凯杰 Biosharp Omega

首页细胞生物学检测Millipore 密理博>

图片仅供参考,请以实物为准
收藏

GST (Glutathione S-Transferase)

价:
0.00
价:
¥0.00

号:12-350

牌:Millipore 密理博

账期 货到付款

EA (预计3-5工作日到货)

亲,想了解价格请QQ咨询客服!

工作时间

周一至周五:9:00-18:00

咨询电话

0771-3293894

在线咨询

客服 郭恒 蔡玉坤 曾宪飞 技术咨询

浏览了该商品的用户还浏览了

Replacement Information
Description
Catalogue Number 12-350
Brand Family Upstate
Trade Name
  • Upstate
Description GST
References
Product Information
Presentation 50mM Tris-HCl, pH 8.0, 5mM 2-mercaptoethanol
Applications
Application GST primarily used in Western Blotting.
Key Applications
  • Western Blotting
Biological Information
Entrez Gene Number
Entrez Gene Summary Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.
Gene Symbol
  • GSTA1
  • GST2
  • H-A
  • GTH1
  • GSTA1-1
  • MGC131939
  • GST-epsilon
UniProt Number
UniProt Summary FUNCTION: SwissProt: P08263 # Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
SIZE: 222 amino acids; 25631 Da
SUBUNIT: Homodimer or heterodimer of GSTA1 and GSTA2.
SUBCELLULAR LOCATION: Cytoplasm.
TISSUE SPECIFICITY: Liver.
DOMAIN: SwissProt: P08263 The C-terminal domain may form a component of the hydrophobic substrate-binding site, but in contrast appears not to be directly involved in GSH binding and is not absolutely essential for catalytic activity.
SIMILARITY: Belongs to the GST superfamily. Alpha family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions 1 year at -70°C
Packaging Information
Material Size 250 µg
Transport Information
Supplemental Information
Specifications

温馨提示:因厂家更改产品包装、产地或者更换随机附件等没有任何提前通知,且每位咨询者购买情况、提问时间等不同,为此以下回复仅对提问者3天内有效,其他网友仅供参考!若由此给您带来不便请多多谅解,谢谢!

我要咨询

咨询内容:
支付方式 货到付款 账期付款

服务热线

0771-3293894