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Qiagen 凯杰 Biosharp Omega

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Ms Dopamine D4 Receptor Control Peptide

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号:AG235

牌:Millipore 密理博

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EA (预计3-5工作日到货)

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Replacement Information
Description
Catalogue Number AG235
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Dopamine D4, Mouse, Ms, Control Peptide for AB1787P
Overview 10 amino acid peptide sequence from the mouse D4 receptor within the 3rd extracellular domain.
References
Product Information
Presentation Liquid in PBS, pH 7.4 containing 0.02% sodium merthiolate.
Applications
Key Applications
  • Cell Function Assay
Application Notes For use in blocking the reactivity of AB1787P.

Optimal working dilution must be determined by the end user.
Biological Information
Concentration 1.0 mg/mL
Entrez Gene Number
Entrez Gene Summary This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.
Gene Symbol
  • DRD4
  • D
  • D4DR
UniProt Number
UniProt Summary FUNCTION: SwissProt: P21917 # This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
SIZE: 467 amino acids; 48361 Da
SUBUNIT: Interacts with CLIC6 (By similarity) and GPRASP1.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
SIMILARITY: SwissProt: P21917 ## Belongs to the G-protein coupled receptor 1 family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size 100 µg
Transport Information
Supplemental Information
Specifications

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