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Neurite Growth Protein L1

市场价：: 0.00

促销价：: ¥0.00

货号：GF220

品牌：Millipore 密理博

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北京朝阳

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EA (预计3-5工作日到货)

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Replacement Information

重要规格表

Species	Source	Purity
Human	Mammalian cells, HEK293 cell line	Greater than 90% by SDS-PAGE and Coomassie blue staining. Fig 1. Western blotting by primary antibody rat anti L1 (Millipore Corp, cat. # MAB5272) and secondary antibody goat anti rat, HRP (Millipore Corp, cat. # AP183P). Single band expected at ~ 200 kDa

Description
Catalogue Number	GF220
Brand Family	Chemicon®
Trade Name	Chemicon
Description	Neurite growth protein L1
Background Information	L1, a cell adhesion molecule of the Ig superfamily (IgCAM) plays a critical role in the formation of neuronal networks. This is reflected by the variety of clinical signs associated with the X-linked recessive neurological disorder that is caused by mutations in the L1 gene. L1 regulates the formation of axon fascicles and promotes neurite outgrowth through interaction with a wide spectrum of binding partners including cell adhesion molecules and extra-cellular matrix components. L1 participates in the signaling of a secreted guidance cue of the Semaphorin family, Sema3A. Three types of experimental evidence support L1 as a key component of the Sema3A receptor complex. Chimeric protein of Human neurite growth protein L1 and Human IgG-Fc γ domain purified using protein A-agarose (Millipore Corp, cat. # 16-125). MW ~ 200 kDa.

References

Product Information
Presentation	100 µg of recombinant protein in 100µl of 1X PBS, 20%(v/v) glycerol. Frozen solution.

Applications
Application	The Neurite Growth Protein L1 is a cell adhesion molecule of the Ig superfamily (IgCAM) plays a critical role in the formation of neuronal networks.
Application Notes	Used at 5 μg/ml (see references 1 and 2). Optimal working concentration must be determined by end user.

Biological Information
Concentration	1 mg/mL
Purity	Greater than 90% by SDS-PAGE and Coomassie blue staining. Fig 1. Western blotting by primary antibody rat anti L1 (Millipore Corp, cat. # MAB5272) and secondary antibody goat anti rat, HRP (Millipore Corp, cat. # AP183P). Single band expected at ~ 200 kDa
Source	Mammalian cells, HEK293 cell line
Specific Activity	See references.

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Shipped on dry ice. Best stored at -80 C for up to 6 months after date of receipt. Thawed aliquots should be used immediately, as repeated freeze/thaw cycles might result in loss of activity.

Packaging Information
Material Size	100 µg

Transport Information

Supplemental Information

Specifications

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