Recombinant, human interferon-β (IFN-β) expressed in CHO cells as a single glycosylated polypeptide containing 166 amino acids. Purified by chromatographic methods. IFN-β is a type I cytokine produced in response to exposure to viruses or double-stranded RNAs. It is also induced by other cytokines, such as TNF and IL-1. It is involved in the regulation of non-specific humoral immune responses and immune responses to viral infections, and thus exhibits anti-viral, anti-proliferative, and immunomodulating properties. The biological activity of IFN-β, unlike IFN-α, is strictly species-specific and will not be active across species.
Catalogue Number
407318
Brand Family
Calbiochem®
Synonyms
Interferon α-2 precursor, IFN-β-1a, rHuIFN-β-1a
References
References
Goebel, M.U., et al. 2005. Physiol. Behav.84, 807. Graber, J., et al. 2005. J. Neuroimmunol.161,169. Mallada-Frechin, J., et al. 2005. Rev. Neurol.40, 482. Patten, S.B., et al. 2005. Mult. Scler.11, 175. Pohl, D., et al. 2005. Neurology64, 888. Schwid, S.R., et al. 2005. Arch. Neurol.62, 785.
Product Information
Form
Lyophilized
Formulation
Lyophilized from 62 mg/ml mannitol, 9.1 mg/ml human albumin, 0.9 mg/ml acetate, pH 7.0-7.2.
Applications
Biological Information
Biological activity
Reported as IU/mg on a lot-specific basis using a viral resistance assay
Purity
≥98% by SDS-PAGE
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code
Blue Ice Only
Toxicity
Standard Handling
Storage
-20°C
Protect from Moisture
Protect from moisture
Do not freeze
Ok to freeze
Special Instructions
Following reconstitution, refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 7 days at 4°C or for up to 4 months at -20°C. Avoid freeze/thaw cycles of solutions.
新浪微博
腾讯微博
QQ空间
客服
