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?-Secretase Inhibitor III

市场价：: 0.00

促销价：: ¥0.00

货号：565780-500UG

品牌：Millipore 密理博

配送至：

北京朝阳

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数量：

EA (预计3-5工作日到货)

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Replacement Information

重要规格表

Empirical Formula
C₄₄H₇₀N₁₀O₁₄

Description
Overview	A substrate analog inhibitor of β-secretase (BACE) that completely blocks the proteolytic activity (at 5 µM) in solubilized membrane fractions from BACE transfected MDCK cells.
Catalogue Number	565780
Brand Family	Calbiochem®
Synonyms	Inhibitor GL189, H-EVNstatineVAEF-NH₂

References
References	Capell, A., et al. 2002. J. Biol. Chem. 277, 5637. Tung, J.S., et al. 2002. J. Med. Chem. 45, 259.

Product Information
ATP Competitive	N
Form	Lyophilized
Formulation	Supplied as a trifluoroacetate salt.
Hill Formula	C₄₄H₇₀N₁₀O₁₄
Chemical formula	C₄₄H₇₀N₁₀O₁₄
Hygroscopic	Hygroscopic
Reversible	N

Applications

Biological Information
Primary Target	BACE
Primary Target IC<sub>50</sub>	Effective concentration: 5 µM completely blocking the proteolytic activity of β-secretase (BACE) in solubilized membrane fractions from BACE transfected MDCK cells
Purity	≥95% by HPLC

Physicochemical Information
Cell permeable	N
Peptide Sequence	H-Glu-Val-Asn-Statine-Val-Ala-Glu-Phe-NH₂

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

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