[关闭]
您好!欢迎来到炼石商城   请登录  注册    兼职小伙伴  
我的购物车
0
Qiagen 凯杰 Biosharp Omega

首页克隆与表达Millipore 密理博>

图片仅供参考,请以实物为准
收藏

SB 220025

价:
0.00
价:
¥0.00

号:559396-500UG

牌:Millipore 密理博

账期 货到付款

EA (预计3-5工作日到货)

亲,想了解价格请QQ咨询客服!

工作时间

周一至周五:9:00-18:00

咨询电话

0771-3293894

在线咨询

客服 郭恒 蔡玉坤 曾宪飞 技术咨询

浏览了该商品的用户还浏览了

Replacement Information

重要规格表

Empirical Formula CAS #
C₁₈H₁₉FN₆ 165806-53-1
Description
Overview A cell-permeable, potent, reversible, ATP-competitive, and specific inhibitor of human p38 MAP Kinase (IC50 = 60 nM). Binds to an extended pocket in the active site of the enzyme. Exhibits over 2000-fold greater selectivity for p38 MAPK over ERK (p42/p44 MAP kinase), 500-fold over PKA, 50-fold over PKC, and >1000-fold over EGFR. Also acts as a potent inhibitor of angiogenesis and as an inhibitor of LPS-induced TNF-α production.

Please note that the molecular weight for this compound is batch-specific due to variable water content.
Catalogue Number 559396
Brand Family Calbiochem®
Synonyms 5-(2-Amino-4-pyrimidinyl)-4-(4-fluorophenyl)-1-(4-piperidinlyl)imidazole, p38 MAP Kinase Inhibitor XIV
References
References Jackson, J.R., et al. 1998. J. Pharmacol. Exp. Ther. 284, 687.
Wang, Z., et al. 1998. Structure 6, 1117.
Product Information
CAS number 165806-53-1
Form White to pale yellow solid
Hill Formula C₁₈H₁₉FN₆
Chemical formula C₁₈H₁₉FN₆
Hygroscopic Hygroscopic
Structure formula Image Structure formula Image
Applications
Biological Information
Primary Target P38MAPK
Primary Target IC<sub>50</sub> 60 nM
Purity ≥98% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special Instructions Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications

温馨提示:因厂家更改产品包装、产地或者更换随机附件等没有任何提前通知,且每位咨询者购买情况、提问时间等不同,为此以下回复仅对提问者3天内有效,其他网友仅供参考!若由此给您带来不便请多多谅解,谢谢!

我要咨询

咨询内容:
支付方式 货到付款 账期付款

服务热线

0771-3293894