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Empirical Formula | CAS # |
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C₃₀H₄₁FN₄O₁₂ | 210344-95-9 |
Description | |
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Overview | A potent, cell-permeable, and irreversible inhibitor of caspase-3 as well as caspase-6, caspase-7, caspase-8, and caspase-10. When using with purified native or recombinant enzyme, pretreatment with an esterase is required. A 5 mM (250 µg/75 µl) solution of Z-DEVD-FMK (Cat. No. 264156) in DMSO is also available. |
Catalogue Number | 264155 |
Brand Family | Calbiochem® |
Synonyms | Z-D(OMe)E(Ome)VD(OMe)-FMK |
Product Information | |
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CAS number | 210344-95-9 |
ATP Competitive | N |
Form | White to slightly brown solid |
Hill Formula | C₃₀H₄₁FN₄O₁₂ |
Chemical formula | C₃₀H₄₁FN₄O₁₂ |
Reversible | N |
Structure formula Image |
Biological Information | |
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Primary Target | caspase-3, caspase-6, caspase-7, caspase-8, caspase-10 |
Purity | ≥90% by TLC |
Physicochemical Information | |
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Cell permeable | Y |
Peptide Sequence | Z-Asp(OCH₃)-Glu(OCH₃)-Val-Asp(OCH₃)-FMK |
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