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NRG1-?1/HRG1-?1 EGF Domain, Human, Recombinant

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号:492029-50UG

牌:Millipore 密理博

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EA (预计3-5工作日到货)

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Replacement Information

重要规格表

Purity
≥97% by SDS-PAGE
Description
Overview Recombinant, human neuregulin 1-β1/heregulin 1-β1 epidermal growth factor-like domain (NRG1-β1/HRG1-β1 EGF Domain), consisting of amino acids 176-246 and expressed in E. coli. All NRG1 isoforms contain an EGF-like domain that is required for binding directly to the ErbB3 or ErbB4 receptor tyrosine kinases.
Catalogue Number 492029
Brand Family Calbiochem®
References
References Buonanno, A., and Fischbach, G.D. 2001. Curr. Opin. Neurobiol. 11, 287.
Adlkofer, K. and Lai, C. 2000. Glia 29, 104.
Garratt, A.N. et al. 2000. BioEssays 22, 987.
Karey, K.P., et al. 1988. Cancer Res. 48, 4083.
Product Information
Form Lyophilized
Formulation Lyophilized from 0.2 µm filtered acetonitrile, TFA, BSA.
Applications
Biological Information
Biological activity ED₅₀ = 0.06-0.3 ng/ml as measured in a serum-free proliferation assay using MCF-7 human breast adenocarcinoma cells.
Purity ≥97% by SDS-PAGE
Physicochemical Information
Contaminants Endotoxin: ≤1.0 EU/µg protein
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special Instructions Following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

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