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(±)-S-Nitroso-N-acetylpenicillamine

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号:487910-1SET

牌:Millipore 密理博

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Replacement Information

重要规格表

Empirical Formula CAS #
C₇H₁₂N₂O₄S 79032-48-7
Description
Overview Nitric oxide donor that mimics the actions of nitric oxide, including relaxation of isolated bovine coronary artery rings (EC50 = 130 nM). Markedly activates soluble guanylate cyclase. Induces apoptosis in mouse thymocytes. Note: 1 set = 4 x 5 mg.
Catalogue Number 487910
Brand Family Calbiochem®
Synonyms SNAP
References
References Nishio, E., et al. 1996. Biochem. Biophys. Res. Commun. 221, 163.
Askew, S.C., et al. 1995. Bioorg. Med. Chem. 3, 1.
Fehsel, K., et al. 1995. J. Immunol. 155, 2858.
Gopalkrishna, R., et al. 1993. J. Biol. Chem. 268, 27180.
Southan, E., and Garthwaite, J. 1991. Neurosci. Lett. 130, 107.
Henry, P.J., et al. 1989. J. Pharmacol. Exp. Ther. 248, 762.
Product Information
CAS number 79032-48-7
ATP Competitive N
Form Pale green solid
Hill Formula C₇H₁₂N₂O₄S
Chemical formula C₇H₁₂N₂O₄S
Reversible N
Structure formula Image Structure formula Image
Applications
Biological Information
Primary Target Nitric oxide donor
Primary Target IC<sub>50</sub> EC50 = 130 nM in relaxation of isolated bovine coronary artery rings
Purity ≥95% by HPLC
Physicochemical Information
Cell permeable N
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R Phrase R: 36/37/38

Irritating to eyes, respiratory system and skin.
S Phrase S: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special Instructions SNAP evolves NO immediately upon solubilization; reconstitute just prior to use.
Packaging Information
Transport Information
Supplemental Information
Specifications

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