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Qiagen 凯杰 Biosharp Omega

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PTEN, His•Tag® and S•Tag™, Human Recombinant, S. frugiperda

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号:481409-10UG

牌:Millipore 密理博

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Replacement Information
Description
Overview Full-length, recombinant, human PTEN (GenBank target symbol = PTEN, ACC No. BC_005821) fused at N-terminus to a His•Tag® and S•Tag sequences and expressed in S. frugiperda insect cells. PTEN is a tumor suppressor that is frequently found mutated in human cancers. It serves as a lipid phosphatase and negative regulator of the PI-3K/Akt pathway. Absence of functional PTEN results in constitutive activation of Akt and mTOR kinases.
Catalogue Number 481409
Brand Family Calbiochem®
Synonyms Phosphatase and Tensin Homolog Deleted on Chromosome 10
References
References Harrington, L.S., et al. 2005. Trends Biochem. Sci. 30, 35.
Osaki, M., et al. 2004. Apoptosis 9, 667.
Lennon, G., et al. 1996. Genomics 33, 151.
Product Information
Unit of Definition One unit is defined as the amount of enzyme required to liberate 1 nmol phosphate from PIP₃ per min at 37°C.
Form Liquid
Formulation In 150 mM NaCl, 50 mM Tris-HCl, 5 mM DTT, 1 mM EDTA, 50% glycerol, pH 7.5.
Applications
Biological Information
Purity ≥80% by SDS-PAGE
Specific Activity ≥75 U/mg protein
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Do not freeze Ok to freeze
Special Instructions Following initial thaw, aliquot and freeze (-70°C).
Packaging Information
Transport Information
Supplemental Information
Specifications

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