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SIRT1 Inhibitor IV, (S)-35

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号:566325-500UG

牌:Millipore 密理博

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Replacement Information

重要规格表

Empirical Formula CAS #
C₁₄H₁₅ClN₂O 848193-72-6
Description
Overview A cell-permeable entiomerically pure compound that is structurally similar to and exhibits similar potency (IC50 = 63 nM) and selectivity as SIRT1 Inhibitor III (Cat. No. 566322). Shown to be orally bioavailable with a serum half-life of 94 min in mice in vivo.
Catalogue Number 566325
Brand Family Calbiochem®
Synonyms (6S)-2-Chloro-5,6,7,8,9,10-hexahydro-cyclohepta[b]indole-6-carboxamide
Application Data
References
References Napper, A.D., et al. 2005. J. Med. Chem. 48, 8045.
Product Information
CAS number 848193-72-6
Form Off-white solid
Hill Formula C₁₄H₁₅ClN₂O
Chemical formula C₁₄H₁₅ClN₂O
Applications
Application SIRT1 Inhibitor IV, (S)-35, CAS 848193-72-6, is a cell-permeable, entiomerically pure compound that displays similar potency (IC50 = 63 nM) and selectivity as SIRT1 Inhibitor III (Cat. No. 566322).
Biological Information
Purity ≥96% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R Phrase R: 22-36/37/38

Harmful if swallowed.
Irritating to eyes, respiratory system and skin.
S Phrase S: 26-36-45

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special Instructions Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications

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