0
| Replacement Information |
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| Empirical Formula |
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| C₇₅H₁₁₈N₂₀O₂₂S |
| Description | |
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| Overview | A highly selective NFAT (Nuclear Factor of Activated T-cells) inhibitor that interferes with calcineurin-NFAT interaction without affecting calcineurin (Cat. No. 539568) phosphatase activity. Inhibits NFAT activation and NFAT-dependent expression of endogenous cytokine genes in T cells, without affecting the expression of other cytokines that require calcineurin but not NFAT. |
| Catalogue Number | 480402 |
| Brand Family | Calbiochem® |
| Synonyms | MAGPHPVIVITGPHEE |
| References | |
|---|---|
| References | Noguchi, H., et al. 2004. Nat. Med. 10, 305. Kiani, A., et al. 2001. Blood 98, 1480. Aramburu, J., et al. 1999. Science 285, 2129. |
| Applications |
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| Biological Information | |
|---|---|
| Primary Target | NFAT (Nuclear Factor of Activated T-cells) |
| Purity | ≥95% by HPLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | N |
| Peptide Sequence | H-Met-Ala-Gly-Pro-His-Pro-Val-Ile-Val-Ile-Thr-Gly-Pro-His-Glu-Glu-OH |
| Dimensions |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Safety Information |
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| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
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| Supplemental Information |
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| Specifications |
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