Phosphodiesterase 4B2, His•Tag®, Human, Recombinant, S. frugiperda - 炼石商城

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Phosphodiesterase 4B2, His•Tag®, Human, Recombinant, S. frugiperda

市场价：: 0.00

促销价：: ¥0.00

货号：524736-10U

品牌：Millipore 密理博

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北京朝阳

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Replacement Information

重要规格表

Description
Overview	Full-length, recombinant, human phosphodiesterase 4B2 (accession no. L20971) fused at the N-terminus to a His•Tag^® sequence and expressed in S. frugiperda using a baculovirus expression system. Plays a significant role in the regulation of inflammatory cell activation. PDE4B2 is a predominant isoform in neutrophils and monocytes. Supplied as a partially purified, catalytically active preparation.
Catalogue Number	524736
Brand Family	Calbiochem®
Synonyms	PDE4B2, cAMP-Specific Phosphodiesterase 4B2
Application Data	Phosphodiesterase 4B2 was treated with increasing concentrations of the inhibitor, rolipram, and the activity assayed. the IC₅₀ for this inhibition is 1.77 µM.

References
References	Gibson, L.C.D., et al. 2006. Eur. J. Pharmacol. 538, 39. Smith, P.G., et al. 2005 Blood 105, 308. Baroja, M.L., et al. 1999. J. Immunol. 162, 2016.

Product Information
Activity	≥ 0.25 units/µl
Unit of Definition	One unit is defined as the amount of enzyme that will convert 1 pmol cAMP to AMP per min at 30°C, pH 7.5.
Form	Liquid
Formulation	In 150 mM NaCl, 10 mM Tris, 0.1% NP-40, pH 8.3.

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Product Usage Statements

Storage and Shipping Information
Ship Code	Dry Ice Only
Toxicity	Standard Handling
Storage	≤ -70°C
Avoid freeze/thaw	Avoid freeze/thaw
Do not freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-70°C).

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