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TACE Substrate III, Fluorogenic

市场价：: 0.00

促销价：: ¥0.00

货号：616403-500UG

品牌：Millipore 密理博

配送至：

北京朝阳

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数量：

EA (预计3-5工作日到货)

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Replacement Information

Description
Overview	A fluorescence resonance energy transfer (FRET) peptide substrate for TACE (K_m = 19 µM). Substrate cleavage occurs at the Ala-Val bond. Useful for the screening of TACE and SARS protease 3-CL^PRO inhibitors.
Catalogue Number	616403
Brand Family	Calbiochem®
Synonyms	TNF-α Convertase Enzyme Substrate II, Fluorogenic, DABCYL-LAQAVRSSSR-EDANS, ADAM-17 Substrate II, Fluorogenic

References
References	Bacha, U., et al. 2004. Biochemistry 43, 4906. Patel, I.R., et al. 1998. J. Immunol. 160, 4570.

Product Information
CAS number	396716-14-6
ATP Competitive	N
Form	Red lyophilized solid
Formulation	Supplied as a trifluoroacetate salt.
Hill Formula	C₇₀H₁₀₄N₂₂O₁₈S
Chemical formula	C₇₀H₁₀₄N₂₂O₁₈S
Reversible	N
Sold on the basis of peptide content	Y

Applications

Biological Information
Primary Target	A fluorescence resonance energy transfer (FRET) peptide substrate for TACE
Primary Target IC<sub>50</sub>	Km = 19 µM as a fluorescence resonance energy transfer (FRET) peptide substrate for TACE
Purity	≥95% by HPLC

Physicochemical Information
Cell permeable	N
Emission max.
Excitation max.
Peptide Content	Y
Peptide Sequence	DABCYL-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-EDANS

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Protect from Light	Protect from light
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

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