Aprotinin, Bovine, Recombinant, Nicotiana sp., Animal-Free

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Aprotinin, Bovine, Recombinant, Nicotiana sp., Animal-Free

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货号：616371-1MG

品牌：Millipore 密理博

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Replacement Information

重要规格表

Empirical Formula	CAS #
C₂₈₄H₄₃₂N₈₄O₇₉S₇	9087-70-1

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616371-1MGCN	正在查询供货情况...... — 目前缺货有货停产少量现货供货情况有待确认登录查看库存有货目前缺货有货其余：另行通知其余：另行通知另行通知 <a class="null" href="null">联系客户服务</a> Contact Customer Service <a class="null" href="null">联系客户服务</a> <a class="null" href="null">联系客户服务</a>	塑胶安瓿;塑胶针药瓶	1 mg	正在检索价格...... 无法检索价格。最小订购数量为倍数以订单确认为准更多信息您节约了 ( )。 — Request Pricing 登录查看价格	查看库存情况 —	添加到收藏夹添加到收藏夹添加到我的收藏夹
616371-25MGCN	正在查询供货情况...... — 目前缺货有货停产少量现货供货情况有待确认登录查看库存有货目前缺货有货其余：另行通知其余：另行通知另行通知 <a class="null" href="null">联系客户服务</a> Contact Customer Service <a class="null" href="null">联系客户服务</a> <a class="null" href="null">联系客户服务</a>	玻璃瓶	25 mg	正在检索价格...... 无法检索价格。最小订购数量为倍数以订单确认为准更多信息您节约了 ( )。 — Request Pricing 登录查看价格	查看库存情况 —	添加到收藏夹添加到收藏夹添加到我的收藏夹
616371-5MGCN	正在查询供货情况...... — 目前缺货有货停产少量现货供货情况有待确认登录查看库存有货目前缺货有货其余：另行通知其余：另行通知另行通知 <a class="null" href="null">联系客户服务</a> Contact Customer Service <a class="null" href="null">联系客户服务</a> <a class="null" href="null">联系客户服务</a>	塑胶安瓿;塑胶针药瓶	5 mg	正在检索价格...... 无法检索价格。最小订购数量为倍数以订单确认为准更多信息您节约了 ( )。 — Request Pricing 登录查看价格	查看库存情况 —	添加到收藏夹添加到收藏夹添加到我的收藏夹

Description
Overview	Recombinant, bovine aprotinin supplied without animal-derived components. Aprotinin is a competitive, reversible inhibitor of proteolytic and esterolytic activity. A relatively heat- and acid-stable serine protease inhibitor. Forms a tight complex, blocking the active site of the enzyme. Effective at concentrations equimolar with protease. Inhibits several proteases, including coagulation factors in the prephase of blood clotting, tissue and leukocytic proteinases, chymotrypsin, trypsin (K_d = 5 x 10^-14 M), plasmin (K_d = 2.3 x 10^-10 M), and kallikrein (K_d = 1 x 10^-7 M). Proteases not inhibited by aprotinin include Factor Xa, thrombin, pepsin, papain, and carboxypeptidases A and B. Useful for protein purification and for extending the life of cells in culture by preventing proteolytic damage.
Catalogue Number	616371
Brand Family	Calbiochem®
Synonyms	Pancreatic Trypsin Inhibitor, Trypsin-Kallikrein Inhibitor, Kallikrein-Trypsin Inactivator, Antikrein, Basic Pancreatic Trypsin Inhibitor

References
References	Deutscher, M.P., 1990. Methods Enzymol. 182, 83.

Product Information
CAS number	9087-70-1
Unit of Definition	One TIU (Trypsin Inhibitory Unit) is defined as the amount of aprotinin or product or inhibitor that will decrease the activity of 2 trypsin units by 50% where one trypsin unit will hydrolyze 1 µmol BAPNA per min at 25°C, pH 7.8.
ATP Competitive	N
EC number	2329949
Form	White to yellow powder
Formulation	Contains no animal-derived components.
Hill Formula	C₂₈₄H₄₃₂N₈₄O₇₉S₇
Chemical formula	C₂₈₄H₄₃₂N₈₄O₇₉S₇
Reversible	Y

Applications

Biological Information
Primary Target	chymotrypsin
Primary Target IC<sub>50</sub>	Kd = 5 x 10-14 M, 2.3 x 10-10 M, 1 x 10-7 M against trypsin, plasmin, and kallikrein, respectively
Purity	≥95% by SDS-PAGE
Specific Activity	>5 TIU/mg protein
Concentration Label	Please refer to vial label for lot-specific concentration

Physicochemical Information
Cell permeable	N

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS
RTECS	YN5080000

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Blue Ice Only
Toxicity	Standard Handling
Storage	+2°C to +8°C
Do not freeze	Ok to freeze

Packaging Information

Transport Information

Supplemental Information

Specifications

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Aprotinin, Bovine, Recombinant, Nicotiana sp., Animal-Free

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