Osteopontin, His•Tag®, Mouse, Recombinant, Mouse - 炼石商城

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Osteopontin, His•Tag®, Mouse, Recombinant, Mouse

市场价：: 0.00

促销价：: ¥0.00

货号：499260-50UG

品牌：Millipore 密理博

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北京朝阳

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EA (预计3-5工作日到货)

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Replacement Information

Description
Overview	Recombinant, mouse osteopontin fused at the C-terminus to a His•Tag^® sequence and expressed in NSO-derived Leu¹⁷-Asn²⁹⁴ (Glu99Gly) murine myeloma cells. A secreted, highly acidic, Ca²⁺-binding, RGD-containing, phosphorylated glycoprotein. Chemotactic for macrophages, smooth muscle cells, endothelial cells, and glial cells. Has been shown to inhibit nitric oxide production and cytotoxicity by activated macrophages. Plays a significant role in inducing granulomas of various origin. OPN is also involved in the migration of embryonic fibroblasts, macrophages, and metastatic cells.
Overview	M.W. 65,000 and 30,000 under reducing conditions.
Catalogue Number	499260
Brand Family	Calbiochem®
Synonyms	rmOPN

References
References	Xie, Y., et al. 2001. Kidney Int. 60, 1645. Chiba, S., et al. 2000. Microbiol. Immunol. 44, 319. Miyazaki, Y., et al. 1990. J. Biol. Chem. 265, 14432.

Product Information
Form	Lyophilized
Formulation	Lyophilized from 0.2 µm sterile-filtered PBS, 50 µg BSA/µg rmOPN.

Applications

Biological Information
Biological activity	~200 ng immobilized osteopontin/well will mediate the adhesion of ≥25% of the 293 cells plated at 10⁵ cells/well
Purity	≥95% by SDS-PAGE

Physicochemical Information
Contaminants	Endotoxins: ≤100 pg/µg rmOPN

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	≤ -70°C
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 1 month at 4°C and for up to 3 months at -70°C. Avoid freeze/thaw cycles of stock solutions.

Packaging Information

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Supplemental Information

Specifications

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