Progranulin, CF, Mouse, Recombinant

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Progranulin, CF, Mouse, Recombinant

市场价：: 0.00

促销价：: ¥0.00

货号：537009-50UG

品牌：Millipore 密理博

配送至：

北京朝阳

支付：账期货到付款

数量：

EA (预计3-5工作日到货)

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0771-3293894

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Replacement Information

重要规格表

Purity
≥90% by SDS-PAGE

Description
Overview	Recombinant, mouse progranulin, consisting of amino acids 18-589, fused at the C-terminus to a His•Tag^® sequence, and expressed in NS0-derived mouse myeloma cells. Progranulin is an ubiquitously expressed, secreted glycoprotein that is involved in regulation of cell proliferation.
Catalogue Number	537009
Brand Family	Calbiochem®
Synonyms	PC cell-derived growth factor (PCDGF)

References
References	Liu, Y. et al. 2007. BMC Cancer 7, 22. Xu, K. et al. 2007. J. Biol. Chem. 282, 11347. Barreda, D.R. et al. 2004. Dev. Comp. Immunol. 28, 727. Davidson, B. et al. 2004. Cancer 100, 2139. Sun, X. et al. 2004. Am. J. Respir. Cell Mol. Biol. 30, 510. Gonzalez, E.M. et al. 2003. J. Biol. Chem. 278, 38113. He, Z. et al. 2003. Nat. Med. 9, 225. He, Z. and Bateman, A. 2003. J. Mol. Med. 81, 600. Jones, M.B. et al. 2003. Gynecol. Oncol. 88, S136. Wang, W. et al. 2003. Clin. Cancer Res. 9, 2221. Suzuki, M. and Nishiahara, M. 2002. Mol. Genet. Metab. 75, 31. Zhu, J. et al. 2002. Cell 111, 867. Lu, R. and Serrero, G. 2000. Proc. Natl. Acad. Sci. U.S.A. 97, 3993. Justen, H.P. et al. 2000. Mol. Cell Biol. Res. Commun. 3, 165. Zanocco Marani, T. et al. 1999. Cancer Res. 59, 5331. Zhang, H. and G. Serrero 1998. Proc. Natl. Acad. Sci. U.S.A. 95, 14202. Zhou, J. et al. 1993. J. Biol. Chem. 268, 10863. Plowman, G.D. et al. 1992. J. Biol. Chem. 267, 13073. Bateman, A. et al. 1990. Biochem. Biophys. Res. Commun. 173, 1161.

References

Liu, Y. et al. 2007. BMC Cancer 7, 22.
Xu, K. et al. 2007. J. Biol. Chem. 282, 11347.
Barreda, D.R. et al. 2004. Dev. Comp. Immunol. 28, 727.
Davidson, B. et al. 2004. Cancer 100, 2139.
Sun, X. et al. 2004. Am. J. Respir. Cell Mol. Biol. 30, 510.
Gonzalez, E.M. et al. 2003. J. Biol. Chem. 278, 38113.
He, Z. et al. 2003. Nat. Med. 9, 225.
He, Z. and Bateman, A. 2003. J. Mol. Med. 81, 600.
Jones, M.B. et al. 2003. Gynecol. Oncol. 88, S136.
Wang, W. et al. 2003. Clin. Cancer Res. 9, 2221.
Suzuki, M. and Nishiahara, M. 2002. Mol. Genet. Metab. 75, 31.
Zhu, J. et al. 2002. Cell 111, 867.
Lu, R. and Serrero, G. 2000. Proc. Natl. Acad. Sci. U.S.A. 97, 3993.
Justen, H.P. et al. 2000. Mol. Cell Biol. Res. Commun. 3, 165.
Zanocco Marani, T. et al. 1999. Cancer Res. 59, 5331.
Zhang, H. and G. Serrero 1998. Proc. Natl. Acad. Sci. U.S.A. 95, 14202.
Zhou, J. et al. 1993. J. Biol. Chem. 268, 10863.
Plowman, G.D. et al. 1992. J. Biol. Chem. 267, 13073.
Bateman, A. et al. 1990. Biochem. Biophys. Res. Commun. 173, 1161.

Product Information
Form	Lyophilized
Formulation	Lyophilized from 0.2 µm filtered PBS.

Applications

Biological Information
Biological activity	Significantly enhances neurite outgrowth of E18 rat embryonic cortical neurons using 4-16 µg/ml progranulin immobilized on nitrocelluose-coated microplates.
Purity	≥90% by SDS-PAGE

Physicochemical Information
Contaminants	Endotoxin: ≤1.0 EU/µg protein

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.