Plasminogen Activator Inhibitor-1, Mutant, Human, Recombinant - 炼石商城

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Plasminogen Activator Inhibitor-1, Mutant, Human, Recombinant

市场价：: 0.00

促销价：: ¥0.00

货号：528208-50UG

品牌：Millipore 密理博

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北京朝阳

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EA (预计3-5工作日到货)

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Replacement Information

重要规格表

Description
Overview	Highly purified preparation of an altered form of human PAI-1 containing four mutated amino acids. Mutant PAI-1 is virtually unable to go latent and is stable at elevated temperature and pH for extended periods of time (t_½ = 145 hours at 37°C, pH 7.4). Inhibits uPA (K_i = 5.1 x 10⁶ M^-1 sec^-1) and tPA (K_i = 7.9 x 10⁵ M^-1 sec^-1).
Catalogue Number	528208
Brand Family	Calbiochem®
Synonyms	PAI-1, Mutant

References
References	Berkenpas, M.B., et al. 1995. EMBO J. 14, 2969.

Product Information
ATP Competitive	N
Form	Liquid
Formulation	In 100 mM NaCl, 50 mM sodium phosphate buffer, 1 mM EDTA, pH 6.6.
Reversible	N

Applications

Biological Information
Biological activity	≥90% by uPA assay.
Primary Target	Plasminogen Activator
Primary Target K<sub>i</sub>	5.1 x 106 M-1 sec-1, 7.9 x 105 M-1 sec-1 against uPA and tPA, respectively
Purity	≥95% by SDS-PAGE assay
Concentration Label	Please refer to vial label for lot-specific concentration

Physicochemical Information
Cell permeable	N

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Dry Ice Only
Toxicity	Standard Handling
Storage	≤ -70°C
Avoid freeze/thaw	Avoid freeze/thaw
Do not freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-70°C).

Packaging Information

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Supplemental Information

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