Plasminogen Activator Inhibitor-1, Human, Recombinant

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Plasminogen Activator Inhibitor-1, Human, Recombinant

市场价：: 0.00

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货号：528205-50UG

品牌：Millipore 密理博

配送至：

北京朝阳

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数量：

EA (预计3-5工作日到货)

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Replacement Information

重要规格表

Description
Overview	PAI-1 is the primary inhibitor of both tissue plasminogen activator (tPA) and urokinase (uPA). PAI-1 can exist either in an active inhibitory conformation or in an inactive or latent conformation. This highly purified preparation has not been exposed to denaturing conditions and has been chromatographically purified of latent material. PAI-1 is a marker for acute myocardial infarction and several thrombolytic disorders. Protects platelets against the inhibitory effects of plasma. Reported to be an important prognostic factor in breast cancer patients. PAI-1 is highly stable when stored at or below pH 6.6.
Catalogue Number	528205
Brand Family	Calbiochem®
Synonyms	PAI-1

References
References	Vaughan, D.E., et al. 1995. J. Clin. Invest. 95, 995. Dimitri, G., et al. 1993. Boll. Chim. Farmaceutico 132, 272. Janicke, F., et al. 1993. Breast Cancer Res. Treatment 24, 195. Klasser, K.J., et al. 1993. Coron. Artery Dis. 4, 713. Robbie, L.A., et al. 1993. Thromb. Hemost. 70, 307. Lawrence, D., et al. 1989. Eur. J. Biochem. 186, 523. Collen, D. and Lijnen, H.R. 1987. In The Molecular Basis of Blood Diseases (Stamatoyannopoulus, G., et al. Eds.) W.B. Saunders Ginsberg, D., et al. 1986. J. Clin. Invest. 78, 1673. Vassalli, J.D., et al. 1985. J. Cell Biol. 100, 86.

References

Vaughan, D.E., et al. 1995. J. Clin. Invest. 95, 995.
Dimitri, G., et al. 1993. Boll. Chim. Farmaceutico 132, 272.
Janicke, F., et al. 1993. Breast Cancer Res. Treatment 24, 195.
Klasser, K.J., et al. 1993. Coron. Artery Dis. 4, 713.
Robbie, L.A., et al. 1993. Thromb. Hemost. 70, 307.
Lawrence, D., et al. 1989. Eur. J. Biochem. 186, 523.
Collen, D. and Lijnen, H.R. 1987. In The Molecular Basis of Blood Diseases (Stamatoyannopoulus, G., et al. Eds.) W.B. Saunders
Ginsberg, D., et al. 1986. J. Clin. Invest. 78, 1673.
Vassalli, J.D., et al. 1985. J. Cell Biol. 100, 86.

Product Information
ATP Competitive	N
Form	Liquid
Formulation	In 150 mM NaCl, 50 mM sodium phosphate buffer, 1 mM EDTA, pH 6.6.
Reversible	N

Applications

Biological Information
Biological activity	≥90% by uPA assay
Primary Target	Tissue plasminogen activator (tPA) and urokinase (uPA)
Purity	≥98% by SDS-PAGE

Physicochemical Information
Cell permeable	N

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Dry Ice Only
Toxicity	Standard Handling
Storage	≤ -70°C
Avoid freeze/thaw	Avoid freeze/thaw
Do not freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-70°C).