CHAPS, Molecular Biology Grade

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Qiagen 凯杰 Biosharp Omega

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CHAPS, Molecular Biology Grade

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货号：220201-1KG

品牌：Millipore 密理博

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Replacement Information

重要规格表

Empirical Formula	CAS #
C₃₂H₅₈N₂O₇S	75621-03-3

Description
Overview	Zwitterionic detergent that combines features of bile salts and N-alkyl sulfobetaines. Better at solubilizing proteins than structurally-related carboxylic acid anions and is much more effective at breaking protein-protein interactions than either sodium cholate or TRITON^® X-100 Detergent. Capable of solubilizing the opiate receptor to a state exhibiting reversible binding of opiates. Also, capable of disaggregating cytochrome P450 to its monomeric form without denaturation. Has a small micellar molecular weight and a high critical micellar concentration and can be removed from either gels or protein solutions by dialysis across a membrane. Aggregation number: 4-14.
Overview	Conductivity (1.0 M, 24°C): <100 µmhos.
Catalogue Number	220201
Brand Family	Calbiochem®
Synonyms	3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate

References
References	Chen, Y., et al. 1992. Biochemistry 31, 2415. Ofri, D., et al. 1992. J. Neurochem. 58, 628. Ransom, R.W., et al. 1992. Biochem. Pharmacol. 43, 1823. Simonds, W.F., et al. 1992. Proc. Natl. Acad. Sci. USA 77, 4623. Yannariello-Brown, J., and Weigel, P.H. 1992. Biochemistry 31, 576. Hjelmeland, L.M. 1980. Proc. Natl. Acad. Sci. USA 77, 6368. Simonds, W.F., et al. 1980. Proc. Natl. Acad. Sci. USA 77, 4623.

References

Chen, Y., et al. 1992. Biochemistry 31, 2415.
Ofri, D., et al. 1992. J. Neurochem. 58, 628.
Ransom, R.W., et al. 1992. Biochem. Pharmacol. 43, 1823.
Simonds, W.F., et al. 1992. Proc. Natl. Acad. Sci. USA 77, 4623.
Yannariello-Brown, J., and Weigel, P.H. 1992. Biochemistry 31, 576.
Hjelmeland, L.M. 1980. Proc. Natl. Acad. Sci. USA 77, 6368.
Simonds, W.F., et al. 1980. Proc. Natl. Acad. Sci. USA 77, 4623.

Product Information
CAS number	75621-03-3
Aggregation Number	4 - 14
CMC	6 - 10 mM
Form	White crystalline powder
Hill Formula	C₃₂H₅₈N₂O₇S
Chemical formula	C₃₂H₅₈N₂O₇S
Hygroscopic	Hygroscopic
Micellar weight	6150

Applications

Biological Information
Purity	≥98% by NMR

Physicochemical Information
Contaminants	DNase, RNase, and Protease: none detected

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information
R Phrase	R: 22-36/38 Harmful if swallowed. Irritating to eyes and skin.
S Phrase	S: 26-36 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing.

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Harmful
Storage	+15°C to +30°C
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.