Dkk-2, Mouse, Recombinant

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Dkk-2, Mouse, Recombinant

市场价：: 0.00

促销价：: ¥0.00

货号：371209-10UG

品牌：Millipore 密理博

配送至：

北京朝阳

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数量：

EA (预计3-5工作日到货)

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Replacement Information

重要规格表

Purity
≥95% by SDS-PAGE

Description
Overview	Recombinant, mouse Dickkopf related protein 2 (Dkk-2) consisting of amino acids 26-259 and expressed in S. frugiperda 21 cells with a C-terminal His•Tag^® sequence. Dkk proteins are expressed in mesenchymal tissues and control epithelial transformations.
Catalogue Number	371209
Brand Family	Calbiochem®

References
References	Morvan, F. et al. 2006. J. Bone Miner. Res. 21, 934. Mukhopadhyay, M. et al. 2006. Development 133, 2149. Niehrs, C. 2006. Oncogene 25, 7469. Li, X. et al. 2005. Nat. Genet. 37, 945. Bullock, C.M. et al. 2004. Mol. Pharmacol. 65, 582. Mao, B. and C. Niehrs 2003. Gene 302, 179. Brott, B. and S.Y. Sokol 2002. Mol. Cell. Biol. 22, 6100. Li, L. et al. 2002. J. Biol. Chem. 277, 5977. Mao, B. et al. 2002. Nature 417, 664. Mao, B. et al. 2001. Nature 411, 321. Wu, W. et al. 2000. Current Biol. 10,1611. Monaghan, A.P. et al. 1999. Mech. Dev. 87, 45. Krupnik, V.E. et al. 1999. Gene 238, 301.

References

Morvan, F. et al. 2006. J. Bone Miner. Res. 21, 934.
Mukhopadhyay, M. et al. 2006. Development 133, 2149.
Niehrs, C. 2006. Oncogene 25, 7469.
Li, X. et al. 2005. Nat. Genet. 37, 945.
Bullock, C.M. et al. 2004. Mol. Pharmacol. 65, 582.
Mao, B. and C. Niehrs 2003. Gene 302, 179.
Brott, B. and S.Y. Sokol 2002. Mol. Cell. Biol. 22, 6100.
Li, L. et al. 2002. J. Biol. Chem. 277, 5977.
Mao, B. et al. 2002. Nature 417, 664.
Mao, B. et al. 2001. Nature 411, 321.
Wu, W. et al. 2000. Current Biol. 10,1611.
Monaghan, A.P. et al. 1999. Mech. Dev. 87, 45.
Krupnik, V.E. et al. 1999. Gene 238, 301.

Product Information
Form	Solid
Formulation	Lyophilized from 0.2 µm filtered PBS, BSA.

Applications

Biological Information
Biological activity	Inhibition assay: Inhibits WNT-3a-induced alkaline phosphatase production in MC3T3-E1 mouse osteoblastic cells in the presence of BMP-2. Competetive Binding Assay: Inhibits 50% binding of biotinylated rhDkk-1 (200 ng/ml) to immobilized rmKremen (4 µg/ml) at a concentration of 5-15 µg/ml.
Purity	≥95% by SDS-PAGE

Physicochemical Information
Contaminants	Endotoxin: <1.0 EU per/µg protein

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.