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Gö 7874, Hydrochloride

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号:365252-500UG

牌:Millipore 密理博

账期 货到付款

EA (预计3-5工作日到货)

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Replacement Information

重要规格表

Empirical Formula CAS #
C₂₇H₂₆N₄O₄ · HCl 287935-76-6
Description
Overview A cell-permeable, potent, reversible, ATP-competitive, and selective inhibitor of protein kinase C (IC50 = 4 nM for rat brain PKC). Inhibits protein kinase A (IC50 = 510 nM), protein kinase G (IC50 = 4.8 µM), and myosin light chain kinase (IC50 = 120 nM) at much higher concentrations.
Catalogue Number 365252
Brand Family Calbiochem®
Synonyms MLCK Inhibitor III
References
References Kleinschroth, J., et al. 1995. Bioorg. Med. Chem. Lett. 5, 55.
Product Information
CAS number 287935-76-6
ATP Competitive Y
Form Amber solid
Hill Formula C₂₇H₂₆N₄O₄ · HCl
Chemical formula C₂₇H₂₆N₄O₄ · HCl
Reversible Y
Structure formula Image Structure formula Image
Applications
Biological Information
Primary Target PKC
Primary Target IC<sub>50</sub> 4 nM against rat brain PKC
Purity ≥97% by HPLC
Physicochemical Information
Cell permeable Y
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special Instructions Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

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