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| Replacement Information |
|---|
| Empirical Formula | CAS # |
|---|---|
| C₂₁H₂₈FN₃O₇ | 161401-82-7 |
| Description | |
|---|---|
| Overview | An irreversible general caspase inhibitor. Useful for studies involving recombinant, isolated, and purified caspase enzymes. Unlike Caspase Inhibitor I (Cat. No. 627610), this inhibitor does not require pretreatment with esterase for in vitro studies. A 10 mM (1 mg/221 µl) solution of Caspase Inhibitor VI (Cat. No. 219011) in DMSO is also available. |
| Catalogue Number | 219007 |
| Brand Family | Calbiochem® |
| Synonyms | Z-VAD-FMK |
| References | |
|---|---|
| References | Misaghi, S., et al. 2004. Chem. Biol. 11, 1677. |
| Product Information | |
|---|---|
| CAS number | 161401-82-7 |
| ATP Competitive | N |
| Form | Off-white solid |
| Hill Formula | C₂₁H₂₈FN₃O₇ |
| Chemical formula | C₂₁H₂₈FN₃O₇ |
| Reversible | N |
| Structure formula Image | |
| Applications |
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| Biological Information | |
|---|---|
| Primary Target | general caspase inhibitor |
| Purity | ≥98% by HPLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | N |
| Peptide Sequence | Z-Val-Ala-Asp-CH₂F* |
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