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Qiagen 凯杰 Biosharp Omega

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Helenalin, A. chamissonis ssp. foliosa

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号:374000-500UG

牌:Millipore 密理博

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Replacement Information
Description
Overview A cell-permeable anti-inflammatory sesquiterpene lactone that acts as a specific NF-κB-DNA binding inhibitor by irreversibly alkylating free sulfhydryls of the cysteine residues on the p65 subunit. Exhibits no effect against the DNA-binding activity of the homodimer of p50 subunit, nor does it affect cellular NF-κB activation/nuclear translocation or IκB dissociation/degradation. An excellent research tool for studying NF-κB-mediated biological processes both in cultures in vitro and in animals in vivo.
Catalogue Number 374000
Brand Family Calbiochem®
References
References Boulanger, D., et al. 2007. Vet. Microbiol. 119, 330.
Auld, C.A., et al. 2006. Biochem. Biophys. Res. Commun. 346, 314.
Huang, P.R., et al. 2005. Cancer Lett. 227, 169.
Lyss, G., et al. 1998. J. Biol. Chem. 273, 33508.
Lyss, G., et al. 1997. Biol. Chem. 378, 951.
Product Information
CAS number 6754-13-8
Form White to off-white solid
Hill Formula C₁₅H₁₈O₄
Chemical formula C₁₅H₁₈O₄
Applications
Biological Information
Purity ≥95% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECS BD9630000
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Toxic
Storage -20°C
Protect from Light Protect from light
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special Instructions Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications

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