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Empirical Formula | CAS # |
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C₂₂H₃₁NO₅S | 76343-93-6 |
Description | |
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Overview | A cell-permeable marine toxin that disrupts microfilament organization in cultured cells by the formation of a 1:1 complex with monomeric G-actin (Kd = 200 nM). Also a potent inhibitor of microfilament-mediated processes in sperm, eggs, and embryos. A 1 mM (50 µg/119 µl) solution of Latrunculin A, Latrunculia magnifica Cat. No. 428026 in DMSO is also available. |
Catalogue Number | 428021 |
Brand Family | Calbiochem® |
Product Information | |
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CAS number | 76343-93-6 |
ATP Competitive | N |
Form | White solid |
Hill Formula | C₂₂H₃₁NO₅S |
Chemical formula | C₂₂H₃₁NO₅S |
Reversible | N |
Structure formula Image |
Applications |
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Biological Information | |
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Primary Target | G-actin |
Primary Target IC<sub>50</sub> | Kd = 200 nM in formation of a 1:1 complex with monomeric G-actin |
Purity | ≥95% by HPLC |
Physicochemical Information | |
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Cell permeable | Y |
Dimensions |
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Materials Information |
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Toxicological Information |
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Safety Information according to GHS |
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Safety Information | |
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R Phrase | R: 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. |
S Phrase | S: 36 Wear suitable protective clothing. |
Product Usage Statements |
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Packaging Information | |
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Packaged under inert gas | Packaged under inert gas |
Transport Information |
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Supplemental Information |
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Specifications |
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