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Latrunculin A, Latrunculia magnifica

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号:428021-100UG

牌:Millipore 密理博

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Replacement Information

重要规格表

Empirical Formula CAS #
C₂₂H₃₁NO₅S 76343-93-6
Description
Overview A cell-permeable marine toxin that disrupts microfilament organization in cultured cells by the formation of a 1:1 complex with monomeric G-actin (Kd = 200 nM). Also a potent inhibitor of microfilament-mediated processes in sperm, eggs, and embryos. A 1 mM (50 µg/119 µl) solution of Latrunculin A, Latrunculia magnifica Cat. No. 428026 in DMSO is also available.
Catalogue Number 428021
Brand Family Calbiochem®
References
References Ayscough, K.R., et al. 1997. J. Cell Biol. 137, 399.
Spector, I., et al. 1989. Cell Motil. Cytoskeleton 13, 127.
Coue, M., et al. 1987. FEBS Lett. 213, 316.
Schatten, G., et al. 1986. Exp. Cell Res. 166, 191.
Spector, I., et al. 1983. Science 219, 493.
Product Information
CAS number 76343-93-6
ATP Competitive N
Form White solid
Hill Formula C₂₂H₃₁NO₅S
Chemical formula C₂₂H₃₁NO₅S
Reversible N
Structure formula Image Structure formula Image
Applications
Biological Information
Primary Target G-actin
Primary Target IC<sub>50</sub> Kd = 200 nM in formation of a 1:1 complex with monomeric G-actin
Purity ≥95% by HPLC
Physicochemical Information
Cell permeable Y
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R Phrase R: 20/21/22

Harmful by inhalation, in contact with skin and if swallowed.
S Phrase S: 36

Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special Instructions Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications

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