MMP Substrate III, Fluorogenic - 炼石商城

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MMP Substrate III, Fluorogenic

市场价：: 0.00

促销价：: ¥0.00

货号：444256-500UG

品牌：Millipore 密理博

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北京朝阳

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数量：

EA (预计3-5工作日到货)

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Replacement Information

重要规格表

Description
Overview	A specific fluorogenic resonance energy transfer (FRET) peptide substrate with an MMP cleavable Gly-Leu bond and EDANS/Dabcyl as fluorophore/quencher combination. Useful for the detection of MMP activity [k_cat/K_m = 619,000 M^-1s^-1 for MMP-2, 206,000 M^-1s^-1 for MMP-9, 40,000 M^-1s^-1 for MMP-3, and 21,000 M^-1s^-1 for MMP-1; at 37°C, pH 7.6 ]. Exhibits a high degree of sensitivity that is not affected by optical disturbances in biological media. Also useful for MMP activity measurements in synovial fluid and culture medium.
Catalogue Number	444256
Brand Family	Calbiochem®
Synonyms	DABCYL-GABA-PQGL-E(EDANS)-AK-NH₂, TNO211

References
References	Beekman, B., et al. 1996. FEBS Lett 390, 221.

Product Information
ATP Competitive	N
Form	Red lyophilized solid
Formulation	Supplied as a trifluoroacetate salt.
Hill Formula	C₆₃H₈₈N₁₆O₁₄S
Chemical formula	C₆₃H₈₈N₁₆O₁₄S
Reversible	N

Applications

Biological Information
Primary Target	Detection of MMP activity
Purity	≥97% by HPLC

Physicochemical Information
Cell permeable	N
Emission max.
Excitation max.
Peptide Sequence	DABCYL-GABA-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH₂

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Protect from Light	Protect from light
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

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