Replacement Information |
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Empirical Formula |
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C₇₃H₁₁₈N₁₆O₂₇ |
Description | |
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Overview | A potent inhibitor of the amyloid precursor protein (APP) β-secretase (IC50 = 30 nM). |
Catalogue Number | 171601 |
Brand Family | Calbiochem® |
Synonyms | KTEETSEVN(stat)VAEF |
References | |
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References | Sinha, S., et al. 1999. Nature 402, 537. |
Product Information | |
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ATP Competitive | N |
Form | Lyophilized |
Formulation | Supplied as a trifluoroacetate salt. |
Hill Formula | C₇₃H₁₁₈N₁₆O₂₇ |
Chemical formula | C₇₃H₁₁₈N₁₆O₂₇ |
Hygroscopic | Hygroscopic |
Reversible | N |
Applications |
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Biological Information | |
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Primary Target | APP |
Primary Target IC<sub>50</sub> | 30 nM against amyloid precursor protein (APP) β-secretase |
Purity | ≥98% by HPLC |
Physicochemical Information | |
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Cell permeable | N |
Peptide Sequence | H-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Stat-Val-Ala-Glu-Phe-OH [Stat = (3S,4S)-Statine] |
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Materials Information |
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Toxicological Information |
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Safety Information according to GHS |
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Safety Information |
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Product Usage Statements |
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Supplemental Information |
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Specifications |
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