FGF, Acidic, Mouse, Recombinant

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FGF, Acidic, Mouse, Recombinant

市场价：: 0.00

促销价：: ¥0.00

货号：341589-25UG

品牌：Millipore 密理博

配送至：

北京朝阳

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数量：

EA (预计3-5工作日到货)

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Replacement Information

重要规格表

Purity
≥95% SDS-PAGE

Description
Overview	Recombinant, mouse fibroblast growth factor (FGF) acidic, consisting of amino acids 16-155 and expressed in E. coli, with an N-terminal Met. FGF acidic stimulates proliferation of all cells of mesodermal origin and many cells of ectodermal, neuroectodermal, and endodermal origin. Intracellular FGF acidic inhibits p53 activity and proapoptotic signaling, thereby enabling it to function as a survival factor.
Catalogue Number	341589
Brand Family	Calbiochem®
Synonyms	HBGF-1

References
References	Guerrini, M., et al. 2007. Curr. Pharm. Des. 13, 2045. Nilsen, T., et al. 2007. J. Biol. Chem. 282, 26245. Rajalingam, D., et al. 2007. Biochemistry 46, 9225. Wesche, J., et al. 2006. J. Biol. Chem. 281, 11405. Bouleau, S., et al. 2005. Oncogene 24, 7839. Mohammadi, M., et al. 2005. Cytokine Growth Factor Rev. 16, 107. Presta, M., et al. 2005. Cytokine Growth Factor Rev. 16, 159. Robinson, C.J., et al. 2005. J. Biol. Chem. 280, 42274. Wesche, J., et al. 2005. Biochemistry 44, 6071. Wiedlocha, A., et al. 2005. Mol. Biol. Cell 16, 794. Wiedlocha, A. and V. Sorensen. 2004. Curr. Top. Microbiol. Immunol. 286, 45. Allen, B.L. and A.C. Rapraeger. 2003. J. Cell Biol. 163, 637. Galzie, Z., et al. 1997. Biochem. Cell Biol. 75, 669. Madiai, F., et al. 1996. Gene 179, 231. Imamura, T., et al. 1990. Science 249, 1567.

References

Guerrini, M., et al. 2007. Curr. Pharm. Des. 13, 2045.
Nilsen, T., et al. 2007. J. Biol. Chem. 282, 26245.
Rajalingam, D., et al. 2007. Biochemistry 46, 9225.
Wesche, J., et al. 2006. J. Biol. Chem. 281, 11405.
Bouleau, S., et al. 2005. Oncogene 24, 7839.
Mohammadi, M., et al. 2005. Cytokine Growth Factor Rev. 16, 107.
Presta, M., et al. 2005. Cytokine Growth Factor Rev. 16, 159.
Robinson, C.J., et al. 2005. J. Biol. Chem. 280, 42274.
Wesche, J., et al. 2005. Biochemistry 44, 6071.
Wiedlocha, A., et al. 2005. Mol. Biol. Cell 16, 794.
Wiedlocha, A. and V. Sorensen. 2004. Curr. Top. Microbiol. Immunol. 286, 45.
Allen, B.L. and A.C. Rapraeger. 2003. J. Cell Biol. 163, 637.
Galzie, Z., et al. 1997. Biochem. Cell Biol. 75, 669.
Madiai, F., et al. 1996. Gene 179, 231.
Imamura, T., et al. 1990. Science 249, 1567.

Product Information
Form	Solid
Formulation	Lyophilized from 0.2 µm sterile-filtered solution in MOPS, Na₂SO₄, EDTA, DTT, BSA.

Applications

Biological Information
Biological activity	ED₅₀ = 0.05-0.25 ng/ml, in the presence of 10 µg/ml heparin, as measured in a cell proliferation assay using NR6R-3T3 mouse fibroblasts.
Purity	≥95% SDS-PAGE

Physicochemical Information
Contaminants	Endotoxin: <1.0 EU/µg protein

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.