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ADP-HPD, Dihydrate, Ammonium Salt

市场价：: 0.00

促销价：: ¥0.00

货号：118415-1SET

品牌：Millipore 密理博

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北京朝阳

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EA (预计3-5工作日到货)

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Replacement Information

重要规格表

Empirical Formula
C₁₅H₂₃N₆O₁₂P₂ · NH₄ · 2H₂O

Description
Overview	An amino analog of ADP-ribose that acts as a highly potent, noncompetitive, and specific inhibitor of poly(ADP-ribose) glycohydrolase (PARG; IC₅₀ = 120 nM). Does not affect the activities of either poly(ADP-ribose) polymerase (PARP) or NAD:arginine mono(ADP-ribosyl)-transferase A even at 1 mM concentration. Also acts as an inhibitor of NAD glycohydrolase from Bungarus fasciatus venom at much higher concentrations (IC₅₀ = 260 µM). Note: 1 set = 5 x 60 µg.
Overview	Note: 1 set = 5 x 60 µg
Catalogue Number	118415
Brand Family	Calbiochem®
Synonyms	Adenosine 5ʹ-diphosphate (Hydroxymethyl)pyrrolidinediol, NH₄

References
References	Vispe, S., et al. 2000. Proc. Natl. Acad. Sci. USA 97, 9886. Slama, J.T., et al. 1995. J. Med. Chem. 38, 389. Slama, J.T., et al. 1995. J. Med. Chem. 38, 4332.

Product Information
ATP Competitive	N
Form	White lyophilized solid
Hill Formula	C₁₅H₂₃N₆O₁₂P₂ · NH₄ · 2H₂O
Chemical formula	C₁₅H₂₃N₆O₁₂P₂ · NH₄ · 2H₂O
Hygroscopic	Hygroscopic
Reversible	N
Structure formula Image

Applications
Application	ADP-HPD, Dihydrate, Ammonium Salt, is an amino analog of ADP-ribose that acts as a highly potent, noncompetitive, and specific inhibitor of poly(ADP-ribose) glycohydrolase (PARG; IC50 = 120 nM).

Biological Information
Primary Target	PARG
Primary Target IC<sub>50</sub>	120 nM against poly(ADP-ribose) glycohydrolase (PARG)
Purity	≥95% by HPLC

Physicochemical Information
Cell permeable	N

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Protect from Light	Protect from light
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 1 week at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

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