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| Replacement Information |
|---|
| Empirical Formula | CAS # |
|---|---|
| C₂₅H₂₄N₄O₂ · HCl | 176504-36-2 |
| Description | |
|---|---|
| Overview | An enhanced water-soluble form of Bisindolylmaleimide I (Cat. No. 203290). A reversible and ATP-competitive inhibitor of protein kinase C (Ki = 10 nM). May inhibit protein kinase A at much higher concentrations (Ki = 2 µM). |
| Catalogue Number | 203291 |
| Brand Family | Calbiochem® |
| Synonyms | 2-[1-(3-Dimethylaminopropyl)-1H-indol-3-yl]-3-(1H-indol-3-yl)maleimide, HCl |
| Product Information | |
|---|---|
| CAS number | 176504-36-2 |
| ATP Competitive | Y |
| Form | Orange-red solid |
| Hill Formula | C₂₅H₂₄N₄O₂ · HCl |
| Chemical formula | C₂₅H₂₄N₄O₂ · HCl |
| Reversible | Y |
| Structure formula Image | |
| Applications |
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| Biological Information | |
|---|---|
| Primary Target | Protein kinase C |
| Primary Target K<sub>i</sub> | 10 nM against protein kinase C |
| Purity | ≥95% by HPLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | N |
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