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Qiagen 凯杰 Biosharp Omega

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Adenosine 3?,5?-cyclic Monophosphorothioate, 8-Bromo-, Sp-Isomer, Sodium Salt

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号:116818-5UMOL

牌:Millipore 密理博

账期 货到付款

EA (预计3-5工作日到货)

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Replacement Information

重要规格表

Empirical Formula
C₁₀H₁₀BrN₅O₅PS · Na
Description
Overview A potent cell-permeable, metabolically-stable activator of cAMP-dependent protein kinase (PKA). Induces guanine nucleotide exchange factor activity of GEFI (also known as Epac) and GEFII towards Rap1 both in vivo and in vitro. Significantly more lipophilic and cell-permeable than Sp-cAMPS (Cat. No. 116815). Note: 5 µmol = 2.23 mg.
Catalogue Number 116818
Brand Family Calbiochem®
Synonyms Sp-8-Br-cAMPS, Na
References
References Kawasaki, H., et al. 1998. Science 282, 2275.
de Rooij, J., et al. 1998. Nature 396, 474.
Holen, I., et al. 1996. Eur. J. Biochem. 236, 163.
Schaap, P., et al. 1993. J. Biol. Chem. 268, 6323.
Yokozaki, H., et al. 1992. Cancer Res. 52, 2504.
Product Information
ATP Competitive N
Declaration Sold under license of Patent DE 3,802,865.4 issued to BIOLOG LSI.
Form Lyophilized
Hill Formula C₁₀H₁₀BrN₅O₅PS · Na
Chemical formula C₁₀H₁₀BrN₅O₅PS · Na
Hygroscopic Hygroscopic
Reversible N
Structure formula Image Structure formula Image
Applications
Biological Information
Primary Target PKA
Purity ≥99% by HPLC
Physicochemical Information
Cell permeable Y
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special Instructions Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

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