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PKA Inhibitor 5-24

市场价：: 0.00

促销价：: ¥0.00

货号：116805-500UG

品牌：Millipore 密理博

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北京朝阳

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数量：

EA (预计3-5工作日到货)

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Replacement Information

重要规格表

Empirical Formula	CAS #
C₉₄H₁₄₈N₃₂O₃₁	99534-03-9

Description
Overview	A potent synthetic peptide that is a competitive inhibitor of protein kinase A (K_i = 2.3 nM). Its sequence is derived from the heat-stable skeletal muscle inhibitor protein of PKA. Binds to the catalytic subunit of PKA and displaces the regulatory subunit. Mimics the protein substrate by binding to the catalytic site via the arginine-cluster basic substrate.
Catalogue Number	116805
Brand Family	Calbiochem®
Synonyms	Protein Kinase A Inhibitor 5-24, H-TTYADFIASGRTGRRNAIHD, PKA Inhibitor IV

References
References	Knighton, D.R., et al. 1991. Science 253, 525. Cheng, H.C., et al. 1986. J. Biol. Chem. 261, 989. Rusine, T., et al. 1986. J. Cell Biol. 102, 1630. Wong, Y.S., et al. 1986. J. Biol. Chem. 12089.

Product Information
CAS number	99534-03-9
ATP Competitive	N
Form	Lyophilized
Formulation	Supplied as a trifluoroacetate salt. Sold on the basis of peptide content.
Hill Formula	C₉₄H₁₄₈N₃₂O₃₁
Chemical formula	C₉₄H₁₄₈N₃₂O₃₁
Hygroscopic	Hygroscopic
Reversible	N
Sold on the basis of peptide content	Y

Applications

Biological Information
Primary Target	PKA
Primary Target K<sub>i</sub>	2.3 nM for protein kinase A
Purity	≥95% by HPLC

Physicochemical Information
Cell permeable	N
Peptide Content	Y
Peptide Sequence	H-Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-His-Asp-OH

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.

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