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Qiagen 凯杰 Biosharp Omega

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Activin A, Human, Recombinant, CHO Cells

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号:114700-10UG

牌:Millipore 密理博

账期 货到付款

EA (预计3-5工作日到货)

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Replacement Information

重要规格表

Purity
≥95% by SDS-PAGE
Description
Overview Recombinant, human activin A (disulfide-linked homodimer of two 116-amino acid residue βA subunits) expressed in CHO cells. Mature βA-monomer lacks a potential N-linked glycosylation site and has a calculated molecular weight of 13 kDa. A member of the TGF-β superfamily that is involved in the negative regulation of B lineage lymphocytes. Shown to play an important role in the regulation of hormonogenesis, cellular homeostasis, and differentiation programs. Reported to inhibit endogenous production of IL-6.
Catalogue Number 114700
Brand Family Calbiochem®
References
References Zipori, D., et al. 2001. J. Leukoc. Biol. 69, 867.
Hedger, M.P., et al. 2000. Cytokine 12, 595.
Woodruff, T.K. 1998. Biochem. Pharmacol. 55, 953.
Ying, S.Y., et al. 1997. Proc. Soc. Exp. Biol. Med. 214, 114.
Schwall, R.H., and Lei, C. 1991. Methods Enzymol. 198, 340.
Mason, A., et al. 1986. Biochem. Biophys. Res. Commun. 135, 957.
Product Information
Form Lyophilized
Formulation Lyophilized from sterile filtered 35% acetonitrile, 0.1% TFA, 50 µg BSA/µg Activin A.
Applications
Biological Information
Biological activity ED₅₀ = 0.5-2.0 ng/ml as measured by its ability to induce hemoglobin expression in K562 cells
Purity ≥95% by SDS-PAGE
Physicochemical Information
Contaminants Endotoxin: ≤100 pg/µg Activin A
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage ≤ -70°C
Do not freeze Ok to freeze
Special Instructions Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 3 months at -70°C. Avoid freeze/thaw cycles of solutions.
Packaging Information
Transport Information
Supplemental Information
Specifications

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