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Qiagen 凯杰 Biosharp Omega

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?1-PDX, Human, Recombinant, E. coli

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号:126850-2.5MG

牌:Millipore 密理博

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EA (预计3-5工作日到货)

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Replacement Information

重要规格表

Description
Overview Recombinant protein derived from the bioengineered human α1-antitrypsin gene fused to a His•Tag® sequence and a FLAG®-tag. Contains a minimal furin consensus sequence, RXXR, that effectively blocks the furin-dependent processing of protein precursors (Ki = 600 pM). Extracellular application of α1-PDX can be used to inhibit the processing of biologically significant proteins including viral envelope glycoproteins, bacterial toxins, receptors, and growth factors. Useful for in vivo and in vitro furin inhibition assays.
Catalogue Number 126850
Brand Family Calbiochem®
Synonyms α₁-Antitrypsin Portland
References
References Bassi, D.E., et al. 2001. Proc. Natl. Acad. Sci. USA 98, 10326.
Jean, F., et al. 2000. Proc. Natl. Acad. Sci. USA 97, 2864.
Jean, F., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 7293.
Product Information
ATP Competitive N
Form Lyophilized solid
Formulation Lyophilized from PBS.
Reversible N
Applications
Biological Information
Primary Target Furin-dependent processing of protein precursors
Primary Target K<sub>i</sub> 600 pM against furin-dependent processing of protein precursors
Purity ≥80% by SDS-PAGE
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Cell permeable N
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage +2°C to +8°C
Do not freeze Yes
Special Instructions Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

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