Androgen Receptor, His•Tag®, Human, Recombinant, S. frugiperda

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Androgen Receptor, His•Tag®, Human, Recombinant, S. frugiperda

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货号：346101-5000U

品牌：Millipore 密理博

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北京朝阳

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EA (预计3-5工作日到货)

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Replacement Information

Description
Overview	Recombinant, human androgen receptor (AR) fused at the N-terminus to a Flag-Tag™ sequence and at the C-terminus to His•Tag^® sequence, expressed in S. frugiperda insect cells expressed using a baculovirus expression system, and purified by affinity chromatography. The activity of androgen is mediated by the binding of the intracellular androgen receptor which, when activated, translocates to the nucleus and modulates specific gene transcription by interaction with cis-acting hormone response elements in the target genes.
Catalogue Number	346101
Brand Family	Calbiochem®
Synonyms	AR, Human, Recombinant, Dihydrotestosterone Receptor, Human, Recombinant

References
References	Chen, G., et al. 2005. Prostate 63, 395. Estebanez-Perpina, E., et al. 2005, J. Biol. Chem. 280, 8060. Gao, S., et al. 2005. Mol. Endocrinol. 19, 1792. Hillmer, A.M., et al. 2005. Am. J. Hum. Genet. 77, 140. Kinoshita, M., et al. 2005, Int. J. Urol. 12, 390. Lim, J.T., et al. 2005. Proc. Natl. Acad. Sci. U.S.A. 102, 5156; Marques, R.B., et al. 2005. Int. J. Cancer 117, 221; Metzger, E., et al. 2005. Nature 437, 436; Murthy, S., et al. 2005. Prostate 64, 362; Chang, C., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 5946.

References

Chen, G., et al. 2005. Prostate 63, 395.
Estebanez-Perpina, E., et al. 2005, J. Biol. Chem. 280, 8060.
Gao, S., et al. 2005. Mol. Endocrinol. 19, 1792.
Hillmer, A.M., et al. 2005. Am. J. Hum. Genet. 77, 140.
Kinoshita, M., et al. 2005, Int. J. Urol. 12, 390.
Lim, J.T., et al. 2005. Proc. Natl. Acad. Sci. U.S.A. 102, 5156;
Marques, R.B., et al. 2005. Int. J. Cancer 117, 221;
Metzger, E., et al. 2005. Nature 437, 436;
Murthy, S., et al. 2005. Prostate 64, 362;
Chang, C., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 5946.

Product Information
Activity	1.0 unit is equivalent to 1 ng protein. 20 units are sufficient for a gel-mobility shift assay and 100 units are sufficient for a protein-protein interaction assay.
Unit of Definition	One unit is defined as 1 ng purified protein.
Form	Liquid
Formulation	In 100 mM KCl, 20 mM Tris-HCl, 1 mM DTT, 200 µM EDTA, 20% glycerol, pH 8.0.

Applications

Biological Information
Concentration Label	Please refer to vial label for lot-specific concentration

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Dry Ice Only
Toxicity	Standard Handling
Storage	≤ -70°C
Do not freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-70°C).