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Human Recombinant MeCP2

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货号：14-1067

品牌：Millipore 密理博

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Replacement Information
Description
Catalogue Number 14-1067
Description Human Recombinant MeCP2 (methyl-CpG-binding protein 2)
Overview Human recombinant N-terminal His-tagged MeCP2 expressed in SF9 insect cells and purified by Fast Protein Liquid Chromatography (FPLC).
Background Information MeCP2 (methyl-CpG-binding protein 2) binds methylated CpG sequences in double-stranded DNA resulting in the suppression of transcription. This protein is likely to be involved in the repression of multiple genes. Consistent with this role, mutations of MeCP2 are linked to Rett syndrome, a progressive neurological disorder that is one of the most common causes of mental retardation in females.
References
Product Information
Presentation In a buffer containing 20 mM Tris-Cl pH 7.6, 1 mM EDTA, 0.15 M NaCl, 10% glycerol, 0.5 mM PMSF and 1 mM DTT.
Applications
Application Human recombinant N-terminal His-tagged MeCP2 expressed in SF9 insect cells & purified by Fast Protein Liquid Chromatography (FPLC) & demonstrated to bind methylated DNA
Key Applications
  • DNA-binding Proteins
Biological Information
Concentration 0.5 µg/µL
Purity Greater than 95% purity by SDS PAGE
Molecular Weight 50.2 kDa including histidine tag
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Stable at -80ºC for 6 months from date of receipt.
Packaging Information
Material Size 10 µg
Transport Information
Supplemental Information
Specifications

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