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Human Recombinant H2A.Z

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货号：14-1109

品牌：Millipore 密理博

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Replacement Information

重要规格表

Key Applications
ACT
Description
Catalogue Number 14-1109
Description Human Recombinant Histone H2A.Z
Overview Full-length human recombinant H2A.Z expressed in E. Coli and purified by Fast Protein Liquid Chromatography (FPLC ).
Background Information The histone variant H2A.Z is a evolutionarily conserved histone variant with a calculated molecular weight of13.5 kDa. This variant replaces conventional histone H2A in a subset of nucleosomes. The nucleosome is the basic unit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histones H2A, H2B, H3 and H4. The histone variant H2AZ has emerged as a key regulator of chromatin function and plays an essential role during mammalian development. H2A.Z is involved in transcriptional regulation, antisilencing, silencing, and genome stability.
References
Product Information
Presentation Recombinant protein in a buffer containing 20mM Tris-Cl pH 7.6, 1mM EDTA, 0.15 M NaCl, 10% glycerol, 0.5mM PMSF and 1mM DTT.
Applications
Application Human recombinant histone H2A.Z expressed in E Coli & purified by Fast Protein Liquid Chromatography (FPLC) & verified mass spectrometry.
Key Applications
  • Activity Assay
Application Notes Suitable for in vitro chromatin assembly and enzyme activity assays
Biological Information
Concentration 1.0 µg/µL
Host E. coli
Purity Greater than 98% purity by SDS PAGE
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Stable at -80ºC for 1 year from date of receipt.
Packaging Information
Material Size 100 µg
Transport Information
Supplemental Information
Specifications

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