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Qiagen 凯杰 Biosharp Omega

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NT-3, Human Recombinant Animal Free

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货号：GF308

品牌：Millipore 密理博

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Replacement Information

重要规格表

Source Purity
E. coli Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
Description
Catalogue Number GF308
Description NT-3 Protein, Human Recombinant Animal Free
Alternate Names
  • NT3
  • Neurotrophin 3
  • HDNF
  • Nerve growth factor 2
  • Neurotrophic factor
Background Information Neurotrophin3 (NT3) is a member of the NGF family of neurotrophic factors (also named neurotrophins) that are required for the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous systems. The neurotrophin family is comprised of at least four proteins including NGF, BDNF, NT3, and NT4/5. NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, murine and rat NT-3 are identical. Recombinant human NT-3 is a noncovalently linked homodimer, of two 13.6 kDa polypeptide monomers (240 total amino acid residues).Human and Mouse NT-3 sequences are identical.
References
Product Information
Formulation
Presentation Product is filtered through a 0.2 micron filter before lyophilization. Product is presented in .
Applications
Application Recombinant animal free human NT-3 is manufactured using all non-animal reagents.
Biological Information
Purity Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
Source E. coli
Cross Reactivity None
UniProt Number
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Bioactivity assay: The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found in the range of 20-50 ng/ml.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Store at -20°C for up to 6 months from date of receipt.
Packaging Information
Material Size 10 µg
Transport Information
Supplemental Information
Specifications

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