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Qiagen 凯杰 Biosharp Omega

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TGFa, Human Recombinant Animal Free

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货号：GF313

品牌：Millipore 密理博

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Replacement Information

重要规格表

Source Purity
E. coli Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
Description
Catalogue Number GF313
Description TGF- α Protein, Human Recombinant Animal Free
Alternate Names
  • Transforming growth factor alpha
  • TGFa
  • TGF alpha
  • EGF-like TGF
  • TGF type 1
Background Information Transforming growth factor alpha (TGF-α) is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-α induces transformation anchorage independence in cultured cells. Human, murine and rat TGF-α are cross-species reactive. Recombinant human TGF-α is a 50 amino acid polypeptide (5.5 kDa) which shares approximately 40% sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds.
References
Product Information
Formulation
Presentation Product is filtered through a 0.2 micron filter before lyophilization.
Applications
Application Transforming growth factor alpha (TGF-α) is an EGF-related polypeptide growth factor that signals through the EGF receptor & stimulates the proliferation of a wide range of epidermal & epithelial cells. Manufactured using all non-animal reagents.
Biological Information
Purity Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
Source E. coli
Cross Reactivity Chicken, Mouse, Rat
Entrez Gene Number
UniProt Number
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Bioactivity assay: Determined by its ability to stimulate the proliferation of mouse Balb/c 3T3 cells. The expected ED50 is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Store at -20°C for up to 6 months from date of receipt.
Packaging Information
Material Size 100 µg
Transport Information
Supplemental Information
Specifications

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