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Qiagen 凯杰 Biosharp Omega

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Accessory box for MIC230 CellASIC ONIX Microincubator Controller

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货号：ABI1

品牌：Millipore 密理博

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Replacement Information

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H WB, IHC, IP M Purified Monoclonal Antibody
Description
Catalogue Number MABS273
Description Anti-Abl interactor 1 Antibody, clone W8-3
Alternate Names
  • Abl interactor 1
  • Abelson interactor 1
  • Abi-1
  • AblBP4
  • Eps8 SH3 domain-binding protein
  • Eps8-binding protein
  • Eps8-binding protein
  • Nap1-binding protein
  • Nap1-binding protein
  • Nap1BP
  • Spectrin SH3 domain-binding protein 1
  • e3B1
Background Information Abl interactor 1 (Abelson interactor 1, Abi-1, e3B1) is a member of the family of Abl-interactors and is highly expressed in the brain. Abl interactor 1 is involved in the signaling of ABL1 and ABL2 nonreceptor tyrosine kinases, and the EGF-receptor. The Abl interactor 1 protein contains SH3 domains, and may function as an adaptor protein: It forms a trimeric complex with EPS8 and SOS1 in the transduction of signals from Ras to Rac. Previous studies have suggested that Abl interactor 1 via the Ras and Rac pathways may regulate cell proliferation, cell adhesion, and actin remodeling. Abl interactor 1 is also investigated for its role in tumor suppression.
References
Product Information
Format Purified
Control
  • HeLa cell lysate
Presentation Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Applications
Application Anti-Abl interactor 1 Antibody, clone W8-3.
Key Applications
  • Western Blotting
  • Immunohistochemistry
  • Immunoprecipitation
Application Notes Immunocytochemistry Analysis: A representative lot from an independent laboratory detected Abl interactor 1 in EGF treated Cos-7 cell lysate (Innocenti, M, et al. (2004). Nat Cell Biol. 6(4):319-327.)

Immunoprecipitation Analysis: A representative lot from an independent laboratory immunoprecipitated Abl interactor 1 in GFP-Abl interactor 1 transfected HeLa cells (Innocenti, M, et al. (2004). Nat Cell Biol. 6(4):319-327.)
Biological Information
Immunogen Linear peptide corresponding to human Abl interactor 1.
Clone W8-3
Concentration Please refer to the Certificate of Analysis for the lot-specific concentration.
Host Mouse
Isotype IgG1κ
Species Reactivity
  • Human
Antibody Type Monoclonal Antibody
Entrez Gene Number
Gene Symbol
  • ABI1
  • SSH3BP1
Purification Method Protein G Purified
UniProt Number
Molecular Weight ~55 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Evaluated by Western Blot in HeLa cell lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected Abl interactor 1 in 10 µg of HeLa cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Stable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size 100 µg
Transport Information
Supplemental Information
Specifications

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