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Qiagen 凯杰 Biosharp Omega

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Mouse Leptin ELISA Bulk - 10 Kits

市场价：
43.00
促销价：
¥0.00

货号：EZML-82BK

品牌：Millipore 密理博

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Replacement Information

重要规格表

Analytes Available Species Reactivity Key Applications Detection Methods
Leptin M ELISA Fluorescent, Colorimetric
Description
Catalogue Number EZML-82BK
Description Mouse Leptin ELISA- Space Saver (Bulk) Packaging
Background Information Leptin is synthesized in adipocytes as a 16 kDa molecule and the circulating level is directly proportional to the total amount of fat in the body.
References
Product Information
Detection method Fluorescent Colorimetric
Precision, %
  • Inter-assay: 3.0–4.6
  • Intra-assay: 1.1–1.8
Applications
Application This Mouse Leptin ELISA is used to measure & quantify Leptin levels in Metabolism & Endocrine & Neuroscience research.
Key Applications
  • ELISA
Application Notes Room temperature, 4 hour assay 10 µL sample size
Biological Information
Species Reactivity
  • Mouse
Analytes Available
  • Leptin
Entrez Gene Summary This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.
UniProt Number
UniProt Summary FUNCTION: SwissProt: P41159 # May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
SIZE: 167 amino acids; 18641 Da
SUBUNIT: Interacts with SIGLEC6.
SUBCELLULAR LOCATION: Secreted.
DISEASE:SwissProt: P41159 # Defects in LEP may be a cause of autosomal recessive obesity [MIM:601665].
SIMILARITY: SwissProt: P41159 ## Belongs to the leptin family.
Accuracy
  • 87–100%
Physicochemical Information
Sensitivity
  • 0.05 ng/mL
Linearity of Dilution 100–111%
Standard Curve Range
  • 0.2–30 ng/mL
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • For research use only. Not for use in diagnostic procedures.
Storage and Shipping Information
Packaging Information
Material Size 96-well strip plate
Transport Information
Supplemental Information
Specifications

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