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Qiagen 凯杰 Biosharp Omega

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KDR ACTIVE

市场价：
32.00
促销价：
¥0.00

货号：14-630M

品牌：Millipore 密理博

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Replacement Information
Description
Catalogue Number 14-630M
Brand Family Upstate
Trade Name
  • Upstate
Description KDR Protein, active, 250 µg
Overview human KDR expressed by baculovirus in Sf21 insect cells
References
Product Information
Applications
Application Active, N-terminal His6-tagged, recombinant, human KDR amino acids 790-end,
for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
Source N-terminal His6-tagged, recombinant, human KDR amino acids 790-end
Specific Activity For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Gene Symbol
  • KDR
  • VEGFR-2
  • VEGFR2
  • CD309
  • FLK1
  • VEGFR
Protein Target KDR
Purification Method Ni2+/NTA-agarose
Target Sub-Family TK
UniProt Number
UniProt Summary FUNCTION: SwissProt: P35968 # Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
SIZE: 1356 amino acids; 151527 Da
SUBUNIT: Interacts with SHB upon VEGF activation. Interacts with HIV-1 Tat.
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
SIMILARITY: SwissProt: P35968 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. & Contains 7 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 protein kinase domain.
Molecular Weight 67.9kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance routinely evaluated by phosphorylation of myelin basic protein (MBP)
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions 6 months at -70°C
Packaging Information
Material Size 250 µg
Material Package Also available in 10 μg size (cat#14-630) and in bulk (cat# 14-630-K).
Transport Information
Supplemental Information
Specifications

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