Recombinant Human TGF-beta2

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Recombinant Human TGF-beta2

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货号：GF113

品牌：Millipore 密理博

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北京朝阳

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EA (预计3-5工作日到货)

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重要规格表

Key Applications	Species	Source	Purity
CULT	Human	Baculovirus infected High-5 cells	Greater than 95% by SDS-PAGE. Endotoxin level is less than 0.1 ng per μg (1EU/ug) of TGF-Beta2.

Description
Catalogue Number	GF113
Brand Family	Chemicon®
Trade Name	Chemicon
Description	Transforming Growth Factor-β2 Protein, Recombinant human
Overview	Transforming Growth Factor- beta2 (TGF-beta2) is a member of a superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation and differentiation of normal and transformed cells. Human TGF-beta2 is a 25.0 kDa protein with each subunit containing 112 amino acid residues.
Alternate Names	TGF-beta2

References

Product Information
Presentation	Lyophilized from Sodium Citrate, pH 3.5.

Applications
Application	Transforming Growth Factor-beta2 (TGF-beta2) is a member of a superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation & differentiation of normal & transformed cells.
Key Applications	Cell Culture

Biological Information
Purity	Greater than 95% by SDS-PAGE. Endotoxin level is less than 0.1 ng per μg (1EU/ug) of TGF-Beta2.
Source	Baculovirus infected High-5 cells
Specific Activity	Determined by its ability to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells. The ED(50) was found to be <=0.2ng/ml, corresponding to a specific activity of >=5 x 10e6 units/mg.
Entrez Gene Number	NM_003238.1
Gene Symbol	TGFB2 Polyergin G-TSF TGF-beta-2 MGC116892 TGF-beta2 Cetermin
UniProt Number	P61812
UniProt Summary	FUNCTION: SwissProt: P61812 # TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth. SIZE: 414 amino acids; 47748 Da SUBUNIT: Homodimer; disulfide-linked. SUBCELLULAR LOCATION: Secreted. DISEASE: SwissProt: P61812 # A chromosomal aberration involving TGFB2 is found in a family with Peters anomaly [MIM:604229]. Translocation t(1;7)(q41;p21) with HDAC9. Peters anomaly consists of a central corneal leukoma, absence of the posterior corneal stroma and Descemet membrane, and a variable degree of iris and lenticular attachments to the central aspect of the posterior cornea. SIMILARITY: SwissProt: P61812 ## Belongs to the TGF-beta family.
Stem Cell Type	Mesenchymal Stem Cells

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	The lyophilized powder is stable for a few weeks at room temperature, but best stored at -20°C. Reconstitute with water to a concentration of 50 μg/ml (e.g., 5 μg/100 μl), this will yield a solution of 1 mM citrate buffer pH 3.5 This solution can then be stored at room temperature or at 2-8ºC for 1 month. It is recommended that further dilutions be made into PBS containing 2 mg/ml albumin and stored at -20ºC. Reconstituted human TGF-beta2 should be stored in undiluted aliquots at -20°C for at least 2 months. Avoid repeated freeze/thaw cycles.

Storage and Shipping Information

Storage Conditions

The lyophilized powder is stable for a few weeks at room temperature, but best stored at -20°C. Reconstitute with water to a concentration of 50 μg/ml (e.g., 5 μg/100 μl), this will yield a solution of 1 mM citrate buffer pH 3.5 This solution can then be stored at room temperature or at 2-8ºC for 1 month. It is recommended that further dilutions be made into PBS containing 2 mg/ml albumin and stored at -20ºC. Reconstituted human TGF-beta2 should be stored in undiluted aliquots at -20°C for at least 2 months. Avoid repeated freeze/thaw cycles.