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Recombinant Rat IL-10

市场价：: 0.00

促销价：: ¥0.00

货号：IL035

品牌：Millipore 密理博

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北京朝阳

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EA (预计3-5工作日到货)

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Replacement Information

重要规格表

Key Applications	Species	Purity
CULT	Rat	Greater than 98% by SDS-PAGE and HPLC analysis

Description
Catalogue Number	IL035
Brand Family	Chemicon®
Trade Name	Chemicon
Description	Interleukin-10 Protein, Recombinant rat
Overview	Recombinant Rat Interleukin-10 (IL-10), originally known as Cytokine Synthesis Inhibitory factor (CSIF), is an 18.7 kDa protein of 160 amino acid residues that shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI.
Alternate Names	IL-10

References

Product Information
Presentation	Lyophilized from 5mM Tris, pH 7.2.

Applications
Application	The recombinant rat Interleukin-10 protein, originally known as Cytokine Synthesis Inhibitory Factor (CSIF) is an 18.7 kDa protein of 160 amino acid residues that shares over 80% sequence homology with the Epstein-Barr Virus protein BCRFI.
Key Applications	Cell Culture

Biological Information
Purity	Greater than 98% by SDS-PAGE and HPLC analysis
Specific Activity	The ED(50) was determined by the dose-dependent inhibition of antigen-specific T-cell proliferation is <10 ng/mL.
Entrez Gene Summary	The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
UniProt Number	P15248 P29456
UniProt Summary	FUNCTION: SwissProt: P15248 # Supports IL-2 independent and IL-4 independent growth of helper T-cells. SIZE: 144 amino acids; 15909 Da SUBCELLULAR LOCATION: Secreted. SIMILARITY: SwissProt: P15248 ## Belongs to the IL-7/IL-9 family.
Stem Cell Type	Hematopoietic Stem Cells

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20ºC. We recommend a quick spin followed by reconstitution in 5 mM Tris, pH7.2, to a concentration of 0.1-1.0 mg/mL. This solution can then be diluted into other aqueous buffers and stored at 4ºC for 1 week or -20ºC for future use. Reconstituted IL-10 should be stored in working aliquots at -20°C.

Packaging Information
Material Size	10 µg

Transport Information

Supplemental Information

Specifications

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