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Recombinant Mouse IL-3

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号:IL015

牌:Millipore 密理博

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Replacement Information

重要规格表

Key Applications Species Purity
CULT Mouse Greater than 98% by SDS-PAGE and HPLC analy
Description
Catalogue Number IL015
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Interleukin-3 Protein, Recombinant mouse
Overview Interleukin-3 (IL-3) is a species specific colony stimulating factor which stimulates colony formation of megakaryocytes, neutrophils, and macrophages from bone marrow cultures. Mouse IL-3 is a 15.1 kDa protein containing 135 amino acid residues.
Alternate Names
  • IL-3
References
Product Information
Presentation Sterile filtered and lyophilized protein with no additives.
Applications
Application The recombinant mouse Interleukin-3 protein is a species specific colony stimulating factor which stimulates colony formation of megakaryocytes, neutrophils & macrophages from bone marrow cultures.
Key Applications
  • Cell Culture
Application Notes For most in vitro applications, mouse IL-3 exerts its biological activity in the concentration range of 0.1 to 10.0 ng/mL. Responding cells are (partial list): Certain BM precursor cells.
Biological Information
Purity Greater than 98% by SDS-PAGE and HPLC analy
Specific Activity Chemicon's mouse IL-3 is fully biologically active when compared to standards. The ED(50) as determined by the dose-dependent stimulation of the proliferation of murine M-NFS-60 cells is < 0.05 ng/mL, corresponding to a specific activity of > 2x10e7 units/mg
Entrez Gene Summary The protein encoded by this gene is a potent growth promoting cytokine. This cytokine is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
UniProt Number
UniProt Summary FUNCTION: SwissProt: P08700 # This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes.
SIZE: 152 amino acids; 17233 Da
SUBUNIT: Monomer.
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Activated T-cells, mast cells, natural killer cells.
SIMILARITY: SwissProt: P08700 ## Belongs to the IL-3 family.
Stem Cell Type
  • Hematopoietic Stem Cells
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions The lyophilized powder, though stable at room temperature, is best stored desiccated at -20°C. After a quick spin, reconstitute with sterile water to a concentration of 0.1-1.0 mg/mL. This solution can be diluted into other aqueous buffers and stored at 4°C for one week or at -20°C for future use. Reconstituted mouse IL-3 should be stored in undiluted aliquots at -20°C for up to six months.
Packaging Information
Material Size 10 µg
Transport Information
Supplemental Information
Specifications

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