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Human Fibroblast Growth Factor-21 (FGF-21) ELISA

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货号：EZHFGF21-19K

品牌：Millipore 密理博

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Replacement Information

重要规格表

Analytes Available Species Reactivity Key Applications Detection Methods
FGF-21 H ELISA Fluorescent, Colorimetric
Description
Catalogue Number EZHFGF21-19K
Description Human FGF-21 ELISA Kit
Background Information Recent studies have demonstrated that fibroblast growth factor 21 (FGF-21), a liver derived protein, is able to increase glucose uptake, as well as lower plasma triglyceride levels in an insulin-independent manner. FGF-21 suppresses glucagon release, thereby increasing insulin sensitivity, and reduces the amount of insulin production required by pancreatic β-cells. Unlike insulin, which works in a rapid, hormone-like manner, FGF-21 activity requires several hours, indicating changes in gene expression. While insulin functions through GLUT4 translocation, FGF-21 has been shown to act primarily through the upregulation of adipocyte GLUT1, a transporter that allows glucose to move from the blood into cells even in the absence of insulin. In addition, no significant weight gain was observed when FGF-21 was injected into animals, and mice that had been genetically engineered to overexpress FGF-21 weighed less and had less adipose tissue than the normal controls.
References
Product Information
Detection method Fluorescent Colorimetric
Precision, %
  • Intra-assay: < 6%
  • Inter-assay: < 9%
Applications
Application This Human FGF-21 ELISA Kit is used to measure & quantify FGF-21 levels in Metabolism & Inflammation & Immunology research.
Key Applications
  • ELISA
Application Notes This is a 3-hour assay requiring 50 μL of sample.
Biological Information
Specificity No significant cross-reactivity to the cytokines and metabolic hormones tested was observed.
Species Reactivity
  • Human
Analytes Available
  • FGF-21
Accuracy
  • 83 – 99%
Physicochemical Information
Linearity of Dilution Please contact Technical Service for this information
Standard Curve Range
  • 31.3– 2000 pg/mL
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • For research use only. Not for use in diagnostic procedures.
Storage and Shipping Information
Packaging Information
Material Size 96-well strip plate
Transport Information
Supplemental Information
Specifications

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