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Qiagen 凯杰 Biosharp Omega

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Human Amylin ELISA Kit - COLD PACKS

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货号：EZHA-52K

品牌：Millipore 密理博

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Replacement Information

重要规格表

Analytes Available Species Reactivity Key Applications Detection Methods
Amylin H ELISA Fluorescent, Colorimetric
Description
Catalogue Number EZHA-52K
Description Human Amylin ELISA
Background Information Amylin is a 37 amino acid hormone that is co-secreted with insulin from pancreatic beta cells in response to hyperglycemia.
References
Product Information
Detection method Fluorescent Colorimetric
Precision, %
  • Inter-assay: 5.2–1.3
  • Intra-assay: 1.9 ± 0.7
Applications
Application This Human Amylin ELISA is used to measure & quantify Amylin levels in Metabolism & Endocrine research.
Key Applications
  • ELISA
Application Notes 50 μl plasma or cell culture supernatant 3.5 hour protocol, room temperature
Biological Information
Species Reactivity
  • Human
Analytes Available
  • Amylin
Cross Reactivity This kit will be suitable for the measurement of amylin in rat and feline plasma, however, the precise percent of cross-reactivity is not determined.
Entrez Gene Number
Entrez Gene Summary Islet, or insulinoma, amyloid polypeptide (IAPP, or amylin) is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Recent results suggest that amylin, like the related beta-amyloid (Abeta) assosciated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
Gene Symbol
  • IAPP
  • AMYLIN
  • IAP
  • Amylin
  • DAP
UniProt Number
UniProt Summary FUNCTION: SwissProt: P10997 # Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
SIZE: 89 amino acids; 9806 Da
SUBCELLULAR LOCATION: Secreted.
DISEASE:SwissProt: P10997 # IAPP is the peptide subunit of amyloid found in pancreatic islets of type 2 diabetic patients and in insulinomas.
SIMILARITY: SwissProt: P10997 ## Belongs to the calcitonin family.
Accuracy
  • 96 ± 2.5%
Physicochemical Information
Standard Curve Range
  • 1–100 pM
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • For research use only. Not for use in diagnostic procedures.
Storage and Shipping Information
Packaging Information
Material Size 96-well plate
Transport Information
Supplemental Information
Specifications

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