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Recombinant Mouse GM-CSF

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货号：GF026

品牌：Millipore 密理博

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Replacement Information

重要规格表

Key Applications Species Source Purity
CULT Mouse E.coli Greater than 98% by SDS-PAGE and HPLC analysis
Description
Catalogue Number GF026
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Granulocyte-Macrophage Colony-Stimulating Factor Protein, Recombinant mouse
Overview Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) is a potent species specific stimulator of bone marrow cells. GM-CSF stimulated precursor cells of granulocytes, macrophages, and eosinophils. Murine GM-CSF is a 14.0 kDa protein containing 124 amino acid residues.
Alternate Names
  • GM-CSF
References
Product Information
Presentation Sterile filtered solution lyophilized from 10mM HoAc.
Applications
Application The Granulocyte Macrophage Colony Stimulating Factor protein (GM-CSF protein) is a potent species specific stimulator of bone marrow cells.
Key Applications
  • Cell Culture
Application Notes For most in vitro applications, murine GM-CSF exerts its biological activity in the concentration range of 0.05 to 0.5 ng/mL. Responding cells are (partial list): Certain BM precursor cells
Biological Information
Purity Greater than 98% by SDS-PAGE and HPLC analysis
Source E.coli
Specific Activity Chemicon's mouse GM-CSF is fully biologically active when compared to standards. The ED50 as determined by the dose-dependent stimulation of the proliferation of mouse FDC-P1 cells in <= 0.2 ng/mL, corresponding to a specific activity of >= 5 x 106 units/mg..
Entrez Gene Number
Entrez Gene Summary The protein encoded by this gene is a potent growth promoting cytokine. This cytokine is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
Gene Symbol
  • IL3
  • MGC79399
  • MCGF
  • MULTI-CSF
  • MGC79398
  • IL-3
UniProt Number
UniProt Summary FUNCTION: SwissProt: P08700 # This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes.
SIZE: 152 amino acids; 17233 Da
SUBUNIT: Monomer.
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Activated T-cells, mast cells, natural killer cells.
SIMILARITY: SwissProt: P08700 ## Belongs to the IL-3 family.
Stem Cell Type
  • Hematopoietic Stem Cells
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions The lyophilized murine GM-CSF, though stable at room temperature, is best stored desiccated below 0°C. Reconstitute in water to a concentration of 100 ng/uL. This solution can be diluted into other buffered solutions. Reconstituted murine GM-CSF should be stored in working aliquots at -20°C.
Packaging Information
Material Size 20 µg
Transport Information
Supplemental Information
Specifications

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